{"id":516,"date":"2024-12-21T02:19:52","date_gmt":"2024-12-20T22:19:52","guid":{"rendered":"https:\/\/icu.ge\/?p=516"},"modified":"2024-12-21T02:23:27","modified_gmt":"2024-12-20T22:23:27","slug":"%e1%83%9b%e1%83%90%e1%83%99%e1%83%a0%e1%83%9d%e1%83%a4%e1%83%90%e1%83%92%e1%83%94%e1%83%91%e1%83%98%e1%83%a1-%e1%83%90%e1%83%a5%e1%83%a2%e1%83%98%e1%83%95%e1%83%90%e1%83%aa%e1%83%98%e1%83%98%e1%83%a1","status":"publish","type":"post","link":"https:\/\/icu.ge\/?p=516","title":{"rendered":"\u10db\u10d0\u10d9\u10e0\u10dd\u10e4\u10d0\u10d2\u10d4\u10d1\u10d8\u10e1 \u10d0\u10e5\u10e2\u10d8\u10d5\u10d0\u10ea\u10d8\u10d8\u10e1 \u10e1\u10d8\u10dc\u10d3\u10e0\u10dd\u10db\u10d8 (MAS) \u10d1\u10d0\u10d5\u10e8\u10d5\u10d4\u10d1\u10e8\u10d8"},"content":{"rendered":"\n<figure class=\"wp-block-image size-medium is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/icu.ge\/wp-content\/uploads\/2024\/12\/pedicu-300x300.webp\" alt=\"\" class=\"wp-image-519\" style=\"width:292px;height:auto\" srcset=\"https:\/\/icu.ge\/wp-content\/uploads\/2024\/12\/pedicu-300x300.webp 300w, https:\/\/icu.ge\/wp-content\/uploads\/2024\/12\/pedicu-150x150.webp 150w, https:\/\/icu.ge\/wp-content\/uploads\/2024\/12\/pedicu-768x768.webp 768w, https:\/\/icu.ge\/wp-content\/uploads\/2024\/12\/pedicu.webp 1024w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n\n\n\n<p>\u10db\u10d0\u10d9\u10e0\u10dd\u10e4\u10d0\u10d2\u10d4\u10d1\u10d8\u10e1 \u10d0\u10e5\u10e2\u10d8\u10d5\u10d0\u10ea\u10d8\u10d8\u10e1 \u10e1\u10d8\u10dc\u10d3\u10e0\u10dd\u10db\u10d8 (MAS) \u10d0\u10e0\u10d8\u10e1 \u10d8\u10e8\u10d5\u10d8\u10d0\u10d7\u10d8 \u10f0\u10d8\u10de\u10d4\u10e0\u10d0\u10dc\u10d7\u10d4\u10d1\u10d8\u10d7\u10d8 \u10db\u10d3\u10d2\u10dd\u10db\u10d0\u10e0\u10d4\u10dd\u10d1\u10d0, \u10e0\u10dd\u10db\u10d4\u10da\u10d8\u10ea \u10ec\u10d0\u10e0\u10db\u10dd\u10d0\u10d3\u10d2\u10d4\u10dc\u10e1 \u10ea\u10d8\u10e2\u10dd\u10d9\u10d8\u10dc\u10e3\u10e0\u10d8 \u10e8\u10e2\u10dd\u10e0\u10db\u10d8\u10e1 \u10d4\u10e0\u10d7-\u10d4\u10e0\u10d7 \u10dc\u10d0\u10d8\u10e0\u10e1\u10d0\u10ee\u10d4\u10dd\u10d1\u10d0\u10e1 [1][2]. \u10d4\u10e1 \u10db\u10d3\u10d2\u10dd\u10db\u10d0\u10e0\u10d4\u10dd\u10d1\u10d0 \u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0 \u10d2\u10d0\u10db\u10dd\u10d5\u10da\u10d8\u10dc\u10d3\u10d4\u10e1 \u10e0\u10dd\u10d2\u10dd\u10e0\u10ea \u10d1\u10d0\u10d5\u10e8\u10d5\u10d4\u10d1\u10e8\u10d8, \u10d0\u10e1\u10d4\u10d5\u10d4 \u10db\u10dd\u10d6\u10e0\u10d3\u10d8\u10da\u10d4\u10d1\u10e8\u10d8, \u10e0\u10dd\u10db\u10da\u10d4\u10d1\u10e1\u10d0\u10ea \u10d0\u10e5\u10d5\u10d7 \u10e0\u10d4\u10d5\u10db\u10d0\u10e2\u10dd\u10da\u10dd\u10d2\u10d8\u10e3\u10e0\u10d8 \u10d3\u10d0\u10d0\u10d5\u10d0\u10d3\u10d4\u10d1\u10d4\u10d1\u10d8. MAS-\u10d8\u10e1 \u10d3\u10e0\u10dd\u10e3\u10da\u10d8 \u10d0\u10db\u10dd\u10ea\u10dc\u10dd\u10d1\u10d0 \u10d3\u10d0 \u10d0\u10d2\u10e0\u10d4\u10e1\u10d8\u10e3\u10da\u10d8 \u10db\u10d9\u10e3\u10e0\u10dc\u10d0\u10da\u10dd\u10d1\u10d0 \u10d9\u10e0\u10d8\u10e2\u10d8\u10d9\u10e3\u10da\u10d0\u10d3 \u10db\u10dc\u10d8\u10e8\u10d5\u10dc\u10d4\u10da\u10dd\u10d5\u10d0\u10dc\u10d8\u10d0, \u10e0\u10d0\u10d3\u10d2\u10d0\u10dc \u10db\u10d8\u10e1\u10d8 \u10e3\u10d2\u10e3\u10da\u10d4\u10d1\u10d4\u10da\u10e7\u10dd\u10e4\u10d8\u10e1 \u10e8\u10d4\u10db\u10d7\u10ee\u10d5\u10d4\u10d5\u10d0\u10e8\u10d8 \u10da\u10d4\u10e2\u10d0\u10da\u10dd\u10d1\u10d8\u10e1 \u10db\u10d0\u10e9\u10d5\u10d4\u10dc\u10d4\u10d1\u10d4\u10da\u10d8 8-22%-\u10d8\u10d0 [3][4].<\/p>\n\n\n\n<p>MAS \u10ea\u10dc\u10dd\u10d1\u10d8\u10da\u10d8\u10d0, \u10e0\u10dd\u10d2\u10dd\u10e0\u10ea \u10e0\u10d4\u10d5\u10db\u10d0\u10e2\u10dd\u10da\u10dd\u10d2\u10d8\u10e3\u10e0\u10d8 \u10d3\u10d0\u10d0\u10d5\u10d0\u10d3\u10d4\u10d1\u10d4\u10d1\u10d8\u10e1 \u10d8\u10e8\u10d5\u10d8\u10d0\u10d7\u10d8 \u10d2\u10d0\u10e0\u10d7\u10e3\u10da\u10d4\u10d1\u10d0, \u10db\u10d0\u10d7 \u10e8\u10dd\u10e0\u10d8\u10e1 \u10e1\u10d8\u10e1\u10e2\u10d4\u10db\u10e3\u10e0\u10d8 \u10d3\u10d0\u10e1\u10d0\u10ec\u10e7\u10d8\u10e1\u10d8\u10e1 \u10db\u10e5\u10dd\u10dc\u10d4 \u10d8\u10e3\u10d5\u10d4\u10dc\u10d8\u10da\u10e3\u10e0\u10d8 \u10d8\u10d3\u10d8\u10dd\u10de\u10d0\u10d7\u10d8\u10e3\u10e0\u10d8 \u10d0\u10e0\u10d7\u10e0\u10d8\u10e2\u10d8\u10e1 (SoJIA), \u10e1\u10d8\u10e1\u10e2\u10d4\u10db\u10e3\u10e0\u10d8 \u10ec\u10d8\u10d7\u10d4\u10da\u10d8 \u10db\u10d2\u10da\u10e3\u10e0\u10d0\u10e1 (SLE), \u10d5\u10d0\u10e1\u10d9\u10e3\u10da\u10d8\u10e2\u10d4\u10d1\u10d8\u10e1, \u10d9\u10d0\u10d5\u10d0\u10e1\u10d0\u10d9\u10d8\u10e1 \u10d3\u10d0\u10d0\u10d5\u10d0\u10d3\u10d4\u10d1\u10d8\u10e1 \u10d3\u10d0 \u10d0\u10d5\u10e2\u10dd\u10d8\u10db\u10e3\u10dc\u10e3\u10e0\u10d8 \u10db\u10d3\u10d2\u10dd\u10db\u10d0\u10e0\u10d4\u10dd\u10d1\u10d4\u10d1\u10d8\u10e1 \u10d3\u10e0\u10dd\u10e1.<\/p>\n\n\n\n<p>MAS \u10e8\u10d4\u10e1\u10d0\u10eb\u10da\u10dd\u10d0 \u10d8\u10e7\u10dd\u10e1 \u10d3\u10d0\u10d0\u10d5\u10d0\u10d3\u10d4\u10d1\u10d8\u10e1 \u10de\u10d8\u10e0\u10d5\u10d4\u10da\u10d8 \u10d2\u10d0\u10db\u10dd\u10d5\u10da\u10d8\u10dc\u10d4\u10d1\u10d0 \u10d3\u10d0 \u10db\u10d8\u10e1\u10d8 \u10d2\u10d0\u10d7\u10d5\u10d0\u10da\u10d8\u10e1\u10ec\u10d8\u10dc\u10d4\u10d1\u10d0 \u10e1\u10d0\u10ed\u10d8\u10e0\u10dd\u10d0 \u10d8\u10db \u10e8\u10d4\u10db\u10d7\u10ee\u10d5\u10d4\u10d5\u10d0\u10e8\u10d8\u10ea, \u10d7\u10e3 \u10d1\u10d0\u10d5\u10e8\u10d5\u10e1 \u10e0\u10d4\u10d5\u10db\u10d0\u10e2\u10dd\u10da\u10dd\u10d2\u10d8\u10e3\u10e0\u10d8 \u10d3\u10d0\u10d0\u10d5\u10d0\u10d3\u10d4\u10d1\u10d8\u10e1 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10d6\u10d8 \u10d0\u10e5\u10d0\u10db\u10d3\u10d4 \u10d0\u10e0 \u10f0\u10e5\u10dd\u10dc\u10d8\u10d0. \u10e8\u10dd\u10e2\u10da\u10d0\u10dc\u10d3\u10d8\u10d0\u10e8\u10d8 \u10e9\u10d0\u10e2\u10d0\u10e0\u10d4\u10d1\u10e3\u10da\u10db\u10d0 \u10d1\u10dd\u10da\u10dd \u10d9\u10d5\u10da\u10d4\u10d5\u10d0\u10db [5] \u10d0\u10e9\u10d5\u10d4\u10dc\u10d0, \u10e0\u10dd\u10db MAS-\u10d8\u10e1 \u10e8\u10d4\u10db\u10d7\u10ee\u10d5\u10d4\u10d5\u10d0\u10d7\u10d0 \u10e3\u10db\u10e0\u10d0\u10d5\u10da\u10d4\u10e1\u10dd\u10d1\u10d0 (68%) \u10de\u10d8\u10e0\u10d5\u10d4\u10da\u10d0\u10d3 \u10d0\u10d5\u10d0\u10d3\u10db\u10e7\u10dd\u10e4\u10dd\u10d1\u10d8\u10e1 \u10d2\u10d0\u10db\u10dd\u10d5\u10da\u10d4\u10dc\u10d8\u10e1\u10d0\u10e1 \u10d3\u10d0\u10e4\u10d8\u10e5\u10e1\u10d8\u10e0\u10d3\u10d0. \u10e8\u10d4\u10e1\u10d0\u10d1\u10d0\u10db\u10d8\u10e1\u10d0\u10d3, MAS \u10e3\u10dc\u10d3\u10d0 \u10d2\u10d0\u10dc\u10d8\u10ee\u10d8\u10da\u10d4\u10d1\u10dd\u10d3\u10d4\u10e1 \u10dc\u10d4\u10d1\u10d8\u10e1\u10db\u10d8\u10d4\u10e0 \u10d1\u10d0\u10d5\u10e8\u10d5\u10d7\u10d0\u10dc, \u10e0\u10dd\u10db\u10d4\u10da\u10d8\u10ea \u10db\u10ec\u10d5\u10d0\u10d5\u10d4\u10d3 \u10d0\u10d5\u10d0\u10d3\u10db\u10e7\u10dd\u10e4\u10dd\u10d1\u10e1 \u10ea\u10ee\u10d4\u10da\u10d4\u10d1\u10d8\u10d7 \u10d3\u10d0 \u10d0\u10e0 \u10d0\u10e5\u10d5\u10e1 \u10d3\u10d0\u10d3\u10d2\u10d4\u10dc\u10d8\u10da\u10d8 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10d6\u10d8.<\/p>\n\n\n\n<p>MAS-\u10d8\u10e1 \u10d6\u10e3\u10e1\u10e2\u10d8 \u10e1\u10d8\u10ee\u10e8\u10d8\u10e0\u10d4 \u10e3\u10ea\u10dc\u10dd\u10d1\u10d8\u10d0, \u10d7\u10e3\u10db\u10ea\u10d0 \u10e1\u10d0\u10d5\u10d0\u10e0\u10d0\u10e3\u10d3\u10dd\u10d0, \u10e0\u10dd\u10db \u10d4\u10e1 \u10db\u10d3\u10d2\u10dd\u10db\u10d0\u10e0\u10d4\u10dd\u10d1\u10d0 \u10e1\u10d0\u10d9\u10db\u10d0\u10e0\u10d8\u10e1\u10d0\u10d3 \u10d0\u10e0 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10e1\u10e2\u10d8\u10e0\u10d3\u10d4\u10d1\u10d0 \u10d3\u10d0 \u10e0\u10d4\u10d0\u10da\u10e3\u10e0\u10d0\u10d3 \u10e3\u10e4\u10e0\u10dd \u10d2\u10d0\u10d5\u10e0\u10ea\u10d4\u10da\u10d4\u10d1\u10e3\u10da\u10d8\u10d0, \u10d5\u10d8\u10d3\u10e0\u10d4 \u10d0\u10db\u10df\u10d0\u10db\u10d8\u10dc\u10d3\u10d4\u10da\u10d8 \u10e1\u10e2\u10d0\u10e2\u10d8\u10e1\u10e2\u10d8\u10d9\u10d0 \u10d2\u10d5\u10d7\u10d0\u10d5\u10d0\u10d6\u10dd\u10d1\u10e1.<\/p>\n\n\n\n<p>MAS \u10ea\u10d8\u10e2\u10dd\u10d9\u10d8\u10dc\u10e3\u10e0\u10d8 \u10e8\u10e2\u10dd\u10e0\u10db\u10d8\u10e1 \u10e1\u10de\u10d4\u10e5\u10e2\u10e0\u10e8\u10d8 \u10e8\u10d4\u10d3\u10d8\u10e1:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u10de\u10d8\u10e0\u10d5\u10d4\u10da\u10d0\u10d3\u10d8 \u10f0\u10d4\u10db\u10dd\u10e4\u10d0\u10d2\u10dd\u10ea\u10d8\u10e2\u10e3\u10e0\u10d8 \u10da\u10d8\u10db\u10e4\u10dd\u10f0\u10d8\u10e1\u10e2\u10d8\u10dd\u10ea\u10d8\u10e2\u10dd\u10d6\u10d8 (HLH)<\/strong><\/li>\n\n\n\n<li><strong>\u10db\u10d4\u10dd\u10e0\u10d0\u10d3\u10d8 HLH<\/strong> (\u10d4\u10e1 \u10db\u10dd\u10d8\u10ea\u10d0\u10d5\u10e1 MAS-\u10e1, \u10e2\u10d4\u10e0\u10db\u10d8\u10dc\u10e1, \u10e0\u10dd\u10db\u10d4\u10da\u10d8\u10ea \u10d2\u10d0\u10db\u10dd\u10d8\u10e7\u10d4\u10dc\u10d4\u10d1\u10d0 \u10e0\u10d4\u10d5\u10db\u10d0\u10e2\u10dd\u10da\u10dd\u10d2\u10d8\u10e3\u10e0\u10d8 \u10d3\u10d0\u10e0\u10e6\u10d5\u10d4\u10d5\u10d4\u10d1\u10d8\u10e1 \u10d9\u10dd\u10dc\u10e2\u10d4\u10e5\u10e1\u10e2\u10e8\u10d8, \u10d0\u10e1\u10d4\u10d5\u10d4 HLH-\u10e1, \u10e0\u10dd\u10db\u10d4\u10da\u10d8\u10ea \u10d2\u10d0\u10db\u10dd\u10ec\u10d5\u10d4\u10e3\u10da\u10d8\u10d0 \u10d8\u10dc\u10e4\u10d4\u10e5\u10ea\u10d8\u10d4\u10d1\u10d8\u10d7 (\u10d2\u10d0\u10dc\u10e1\u10d0\u10d9\u10e3\u10d7\u10e0\u10d4\u10d1\u10d8\u10d7 EBV) \u10d3\u10d0 \u10d0\u10d5\u10d7\u10d5\u10d8\u10e1\u10d4\u10d1\u10d8\u10d0\u10dc\u10dd\u10d1\u10d8\u10d7 [6][7][8])<\/li>\n\n\n\n<li><strong>PIMS-TS<\/strong> (\u10d1\u10d0\u10d5\u10e8\u10d5\u10d7\u10d0 \u10db\u10e3\u10da\u10e2\u10d8\u10e1\u10d8\u10e1\u10e2\u10d4\u10db\u10e3\u10e0\u10d8 \u10d0\u10dc\u10d7\u10d4\u10d1\u10d8\u10d7\u10d8 \u10e1\u10d8\u10dc\u10d3\u10e0\u10dd\u10db\u10d8, \u10e0\u10dd\u10db\u10d4\u10da\u10d8\u10ea \u10d3\u10e0\u10dd\u10d4\u10d1\u10d8\u10d7 \u10d0\u10e1\u10dd\u10ea\u10d8\u10e0\u10d3\u10d4\u10d1\u10d0 COVID-19-\u10d7\u10d0\u10dc). \u10d4\u10e1 \u10e1\u10d8\u10dc\u10d3\u10e0\u10dd\u10db\u10d8 \u10ea\u10dc\u10dd\u10d1\u10d8\u10da\u10d8\u10d0 \u10e0\u10dd\u10d2\u10dd\u10e0\u10ea MIS-C (\u10d1\u10d0\u10d5\u10e8\u10d5\u10d4\u10d1\u10e8\u10d8) \u10d3\u10d0 \u10db\u10dd\u10d6\u10e0\u10d3\u10d8\u10da\u10d7\u10d0 \u10db\u10e1\u10d2\u10d0\u10d5\u10e1\u10d8 \u10db\u10d3\u10d2\u10dd\u10db\u10d0\u10e0\u10d4\u10dd\u10d1\u10d0 \u10d0\u10e6\u10ec\u10d4\u10e0\u10d8\u10da\u10d8\u10d0 MIS-A-\u10e1 \u10e1\u10d0\u10ee\u10d4\u10da\u10d8\u10d7.<\/li>\n<\/ul>\n\n\n\n<p>\u10d0\u10db \u10d2\u10d0\u10d8\u10d3\u10da\u10d0\u10d8\u10dc\u10d8\u10e1 \u10db\u10d8\u10d6\u10d0\u10dc\u10d8\u10d0, \u10db\u10d0\u10d9\u10e0\u10dd\u10e4\u10d0\u10d2\u10d4\u10d1\u10d8\u10e1 \u10d0\u10e5\u10e2\u10d8\u10d5\u10d0\u10ea\u10d8\u10d8\u10e1 \u10e1\u10d8\u10dc\u10d3\u10e0\u10dd\u10db\u10d8\u10e1 (MAS) \u10d2\u10d0\u10dc\u10ee\u10d8\u10da\u10d5\u10d0 \u10e0\u10d4\u10d5\u10db\u10d0\u10e2\u10dd\u10da\u10dd\u10d2\u10d8\u10e3\u10e0\u10d8 \u10d3\u10d0\u10d0\u10d5\u10d0\u10d3\u10d4\u10d1\u10d4\u10d1\u10d8\u10e1 \u10d9\u10dd\u10dc\u10e2\u10d4\u10e5\u10e1\u10e2\u10e8\u10d8. \u10d8\u10db \u10e8\u10d4\u10db\u10d7\u10ee\u10d5\u10d4\u10d5\u10d0\u10e8\u10d8, \u10d7\u10e3 \u10d1\u10d0\u10d5\u10e8\u10d5\u10e1 \u10d0\u10e0 \u10d0\u10e5\u10d5\u10e1 \u10d3\u10d0\u10d3\u10d2\u10d4\u10dc\u10d8\u10da\u10d8 \u10eb\u10d8\u10e0\u10d8\u10d7\u10d0\u10d3\u10d8 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10d6\u10d8, \u10e3\u10dc\u10d3\u10d0 \u10d2\u10d0\u10e2\u10d0\u10e0\u10d3\u10d4\u10e1 \u10d3\u10d8\u10e4\u10d4\u10e0\u10d4\u10dc\u10ea\u10d8\u10d0\u10da\u10e3\u10e0\u10d8 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10d6\u10d8, \u10e0\u10dd\u10db\u10d4\u10da\u10d8\u10ea \u10db\u10dd\u10d8\u10ea\u10d0\u10d5\u10e1 \u10de\u10d8\u10e0\u10d5\u10d4\u10da\u10d0\u10d3 \u10d0\u10dc \u10db\u10d4\u10dd\u10e0\u10d0\u10d3 \u10f0\u10d4\u10db\u10dd\u10e4\u10d0\u10d2\u10dd\u10ea\u10d8\u10e2\u10e3\u10e0\u10d8 \u10da\u10d8\u10db\u10e4\u10dd\u10f0\u10d8\u10e1\u10e2\u10d8\u10dd\u10ea\u10d8\u10e2\u10dd\u10d6\u10e1 (HLH) \u10d3\u10d0 MAS-\u10e1, \u10e0\u10dd\u10d2\u10dd\u10e0\u10ea \u10e0\u10d4\u10d5\u10db\u10d0\u10e2\u10dd\u10da\u10dd\u10d2\u10d8\u10e3\u10e0\u10d8 \u10d3\u10d0\u10d0\u10d5\u10d0\u10d3\u10d4\u10d1\u10d8\u10e1 \u10e1\u10d0\u10ec\u10e7\u10d8\u10e1\u10d8 \u10d2\u10d0\u10db\u10dd\u10d5\u10da\u10d8\u10dc\u10d4\u10d1\u10d8\u10e1 \u10dc\u10d0\u10ec\u10d8\u10da\u10e1.<\/p>\n\n\n\n<p><strong>\u10d3\u10d4\u10e4\u10d8\u10dc\u10d8\u10ea\u10d8\u10d0<\/strong><\/p>\n\n\n\n<p><strong>\u10da\u10d0\u10d1\u10dd\u10e0\u10d0\u10e2\u10dd\u10e0\u10d8\u10e3\u10da\u10d8 \u10d0\u10dc\u10d0\u10da\u10d8\u10d6\u10d4\u10d1\u10d8:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u10e4\u10d4\u10e0\u10d8\u10e2\u10d8\u10dc\u10d8<\/strong>: \u10e3\u10e4\u10e0\u10dd \u10db\u10d0\u10e6\u10d0\u10da\u10d8\u10d0, \u10d5\u10d8\u10d3\u10e0\u10d4 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10d6\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1 \u10db\u10dd\u10e1\u10d0\u10da\u10dd\u10d3\u10dc\u10d4\u10da\u10d8\u10d0 (\u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0 \u10eb\u10d0\u10da\u10d8\u10d0\u10dc \u10db\u10d0\u10e6\u10d0\u10da\u10d8 \u10d8\u10e7\u10dd\u10e1, \u10db\u10d0\u10d2\u10e0\u10d0\u10db MAS \u10e3\u10dc\u10d3\u10d0 \u10d2\u10d0\u10dc\u10d8\u10ee\u10d8\u10da\u10d4\u10d1\u10dd\u10d3\u10d4\u10e1 \u10db\u10d0\u10e8\u10d8\u10dc\u10d0\u10ea \u10d9\u10d8, \u10e0\u10dd\u10ea\u10d0 \u10d3\u10dd\u10dc\u10d4 \u2265500 \u03bcg\/l)[9];<\/li>\n\n\n\n<li><strong>\u10d3\u10d0\u10d1\u10d0\u10da\u10d8 \u10d0\u10dc \u10e8\u10d4\u10db\u10ea\u10d8\u10e0\u10d4\u10d1\u10d0\u10d3\u10d8 \u10d4\u10d3\u10e1-\u10d8<\/strong> (\u10d4.\u10ec. ESR), \u10d2\u10d0\u10dc\u10e1\u10d0\u10d9\u10e3\u10d7\u10e0\u10d4\u10d1\u10d8\u10d7 \u10d0\u10e5\u10e2\u10d8\u10e3\u10e0\u10d8 \u10d0\u10dc\u10d7\u10d4\u10d1\u10d8\u10d7\u10d8 \u10d3\u10d0\u10d0\u10d5\u10d0\u10d3\u10d4\u10d1\u10d8\u10e1 \u10d0\u10dc \u10db\u10d0\u10e6\u10d0\u10da\u10d8 CRP-\u10d8\u10e1 \u10d9\u10dd\u10dc\u10e2\u10d4\u10e5\u10e1\u10e2\u10e8\u10d8;<\/li>\n\n\n\n<li><strong>\u10d3\u10d0\u10d1\u10d0\u10da\u10d8 \u10da\u10d4\u10d8\u10d9\u10dd\u10ea\u10d8\u10e2\u10d4\u10d1\u10d8\u10e1 \u10e0\u10d0\u10dd\u10d3\u10d4\u10dc\u10dd\u10d1\u10d0<\/strong>;<\/li>\n\n\n\n<li><strong>\u10d3\u10d0\u10d1\u10d0\u10da\u10d8\/\u10e8\u10d4\u10db\u10ea\u10d8\u10e0\u10d4\u10d1\u10d0\u10d3\u10d8\/\u10dc\u10dd\u10e0\u10db\u10d0\u10da\u10e3\u10e0\u10d8 \u10d7\u10e0\u10dd\u10db\u10d1\u10dd\u10ea\u10d8\u10e2\u10d4\u10d1\u10d8\u10e1 \u10e0\u10d0\u10dd\u10d3\u10d4\u10dc\u10dd\u10d1\u10d0<\/strong>.<\/li>\n\n\n\n<li><strong>\u10d3\u10d0\u10d1\u10d0\u10da\u10d8\/\u10e8\u10d4\u10db\u10ea\u10d8\u10e0\u10d4\u10d1\u10d0\u10d3\u10d8\/\u10dc\u10dd\u10e0\u10db\u10d0\u10da\u10e3\u10e0\u10d8 \u10e4\u10d8\u10d1\u10e0\u10d8\u10dc\u10dd\u10d2\u10d4\u10dc\u10d8<\/strong>;<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:700\"><strong>\u10d9\u10dd\u10d0\u10d2\u10e3\u10da\u10d0\u10ea\u10d8<\/strong>\u10d8\u10e1 \u10d3\u10d0\u10e0\u10e6\u10d5\u10d4\u10d5\u10d0;<\/li>\n\n\n\n<li><strong>LDH-\u10d8\u10e1 \u10db\u10dd\u10db\u10d0\u10e2\u10d4\u10d1\u10e3\u10da\u10d8 \u10d3\u10dd\u10dc\u10d4<\/strong>;<\/li>\n\n\n\n<li><strong>AST, ALT, GGT, \u10d1\u10d8\u10da\u10d8\u10e0\u10e3\u10d1\u10d8\u10dc\u10d8\u10e1 \u10db\u10dd\u10db\u10d0\u10e2\u10d4\u10d1\u10d0<\/strong>;<\/li>\n\n\n\n<li><strong>\u10db\u10d0\u10e6\u10d0\u10da\u10d8 \u10e2\u10e0\u10d8\u10d2\u10da\u10d8\u10ea\u10d4\u10e0\u10d8\u10d3\u10d4\u10d1\u10d8<\/strong>;<\/li>\n\n\n\n<li><strong>\u10d3\u10d0\u10d1\u10d0\u10da\u10d8 \u10dc\u10d0\u10e2\u10e0\u10d8\u10e3\u10db\u10d8<\/strong>;<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:700\"><strong>\u10eb\u10d5\u10da\u10d8\u10e1 \u10e2\u10d5\u10d8\u10dc\u10d8\u10e1 \u10d0\u10e1\u10de\u10d8\u10e0\u10d0\u10ea\u10d8<\/strong>\u10e3\u10da\u10d8 \u10d1\u10d8\u10dd\u10e4\u10e1\u10d8\u10d0 \u10d0\u10e9\u10d5\u10d4\u10dc\u10d4\u10d1\u10e1 \u10f0\u10d4\u10db\u10dd\u10e4\u10d0\u10d2\u10dd\u10ea\u10d8\u10e2\u10dd\u10d6\u10e1 (\u10d4\u10e1 \u10e7\u10dd\u10d5\u10d4\u10da\u10d7\u10d5\u10d8\u10e1 \u10d0\u10e0 \u10d5\u10da\u10d8\u10dc\u10d3\u10d4\u10d1\u10d0 \u10d3\u10d0 \u10e1\u10d0\u10ed\u10d8\u10e0\u10dd\u10d0 \u10db\u10ee\u10dd\u10da\u10dd\u10d3 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10e1\u10e2\u10d8\u10d9\u10e3\u10e0\u10d8 \u10d2\u10d0\u10e3\u10e0\u10d9\u10d5\u10d4\u10d5\u10da\u10dd\u10d1\u10d8\u10e1 \u10e8\u10d4\u10db\u10d7\u10ee\u10d5\u10d4\u10d5\u10d0\u10e8\u10d8).<\/li>\n<\/ul>\n\n\n\n<p><strong>\u10d9\u10da\u10d8\u10dc\u10d8\u10d9\u10e3\u10e0\u10d8 \u10dc\u10d8\u10e8\u10dc\u10d4\u10d1\u10d8:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u10ea\u10ee\u10d4\u10da\u10d4\u10d1\u10d0<\/strong> (\u10ee\u10e8\u10d8\u10e0\u10d0\u10d3 \u10db\u10d0\u10e6\u10d0\u10da\u10d8 \u10d3\u10d0 \u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0 \u10e8\u10d4\u10e3\u10de\u10dd\u10d5\u10d0\u10e0\u10d8 \u10d8\u10e7\u10dd\u10e1);<\/li>\n\n\n\n<li><strong>\u10d2\u10d0\u10db\u10dd\u10dc\u10d0\u10e7\u10d0\u10e0\u10d8<\/strong>;<\/li>\n\n\n\n<li><strong>\u10f0\u10d4\u10de\u10d0\u10e2\u10dd\u10e1\u10de\u10da\u10d4\u10dc\u10dd\u10db\u10d4\u10d2\u10d0\u10da\u10d8\u10d0<\/strong> (\u10d0\u10ee\u10d0\u10da\u10d8);<\/li>\n\n\n\n<li><strong>\u10d0\u10e0\u10d7\u10e0\u10d8\u10e2\u10d8<\/strong>;<\/li>\n\n\n\n<li><strong>\u10dc\u10d4\u10d5\u10e0\u10dd\u10da\u10dd\u10d2\u10d8\u10e3\u10e0\u10d8 \u10db\u10d0\u10dc\u10d8\u10e4\u10d4\u10e1\u10e2\u10d0\u10ea\u10d8\u10d4\u10d1\u10d8<\/strong>: \u10d2\u10d0\u10e6\u10d8\u10d6\u10d8\u10d0\u10dc\u10d4\u10d1\u10d0\u10d3\u10dd\u10d1\u10d0, \u10d3\u10d4\u10d6\u10dd\u10e0\u10d8\u10d4\u10dc\u10e2\u10d0\u10ea\u10d8\u10d0, \u10da\u10d4\u10d7\u10d0\u10e0\u10d2\u10d8\u10d0, \u10d7\u10d0\u10d5\u10d8\u10e1 \u10e2\u10d9\u10d8\u10d5\u10d8\u10da\u10d8, \u10d9\u10e0\u10e3\u10dc\u10e9\u10ee\u10d5\u10d4\u10d1\u10d8, \u10d9\u10dd\u10db\u10d0.<\/li>\n<\/ul>\n\n\n\n<p><strong>\u10e1\u10d0\u10e1\u10ec\u10e0\u10d0\u10e4\u10dd \u10d2\u10d0\u10db\u10dd\u10d9\u10d5\u10da\u10d4\u10d5\u10d4\u10d1\u10d8<\/strong><\/p>\n\n\n\n<p>MAS-\u10d8\u10e1 \u10d4\u10ed\u10d5\u10d8\u10e1 \u10e8\u10d4\u10db\u10d7\u10ee\u10d5\u10d4\u10d5\u10d0\u10e8\u10d8 \u10d4\u10e1 \u10d0\u10dc\u10d0\u10da\u10d8\u10d6\u10d4\u10d1\u10d8 \u10e7\u10dd\u10d5\u10d4\u10da\u10d3\u10e6\u10d8\u10e3\u10e0\u10d0\u10d3 \u10e3\u10dc\u10d3\u10d0 \u10d2\u10d0\u10dc\u10db\u10d4\u10dd\u10e0\u10d3\u10d4\u10e1, \u10e0\u10d0\u10d3\u10d2\u10d0\u10dc \u10e2\u10d4\u10dc\u10d3\u10d4\u10dc\u10ea\u10d8\u10d4\u10d1\u10d8 \u10e3\u10e4\u10e0\u10dd \u10d8\u10dc\u10e4\u10dd\u10e0\u10db\u10d0\u10e2\u10d8\u10e3\u10da\u10d8\u10d0, \u10d5\u10d8\u10d3\u10e0\u10d4 \u10db\u10ee\u10dd\u10da\u10dd\u10d3 \u10d0\u10d1\u10e1\u10dd\u10da\u10e3\u10e2\u10e3\u10e0\u10d8 \u10db\u10d0\u10e9\u10d5\u10d4\u10dc\u10d4\u10d1\u10da\u10d4\u10d1\u10d8:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u10e4\u10d4\u10e0\u10d8\u10e2\u10d8\u10dc\u10d8<\/strong> \u2013 \u10da\u10d0\u10d1\u10dd\u10e0\u10d0\u10e2\u10dd\u10e0\u10d8\u10d0\u10e1 \u10e3\u10dc\u10d3\u10d0 \u10d4\u10ea\u10dc\u10dd\u10d1\u10dd\u10e1, \u10e0\u10dd\u10db \u10d0\u10dc\u10d0\u10da\u10d8\u10d6\u10d8 \u10e1\u10d0\u10e1\u10ec\u10e0\u10d0\u10e4\u10dd\u10d3 \u10e9\u10d0\u10e2\u10d0\u10e0\u10d3\u10d4\u10e1;<\/li>\n\n\n\n<li><strong>\u10e1\u10e0\u10e3\u10da\u10d8 \u10e1\u10d8\u10e1\u10ee\u10da\u10d8\u10e1 \u10d0\u10dc\u10d0\u10da\u10d8\u10d6\u10d8 (CBC)<\/strong>;<\/li>\n\n\n\n<li><strong>\u10d4\u10d3\u10e1-\u10d8 (ESR) \u10d3\u10d0 CRP<\/strong>.<\/li>\n\n\n\n<li><strong>\u10d9\u10dd\u10d0\u10d2\u10e3\u10da\u10d0\u10ea\u10d8\u10d8\u10e1 \u10e1\u10d9\u10e0\u10d8\u10dc\u10d8\u10dc\u10d2\u10d8<\/strong>, \u10db\u10d0\u10d7 \u10e8\u10dd\u10e0\u10d8\u10e1 \u10e4\u10d8\u10d1\u10e0\u10d8\u10dc\u10dd\u10d2\u10d4\u10dc\u10d8\u10e1 \u10d3\u10dd\u10dc\u10d4.<\/li>\n\n\n\n<li style=\"font-style:normal;font-weight:700\"><strong>D-\u10d3\u10d8\u10db\u10d4\u10e0<\/strong>\u10d8;<\/li>\n\n\n\n<li><strong>\u10e2\u10e0\u10d8\u10d2\u10da\u10d8\u10ea\u10d4\u10e0\u10d8\u10d3\u10d4\u10d1\u10d8<\/strong>;<\/li>\n\n\n\n<li><strong>\u10d7\u10d8\u10e0\u10d9\u10db\u10da\u10d4\u10d1\u10d8\u10e1\u10d0 \u10d3\u10d0 \u10e6\u10d5\u10d8\u10eb\u10da\u10d8\u10e1 \u10e4\u10e3\u10dc\u10e5\u10ea\u10d8\u10e3\u10e0\u10d8 \u10e2\u10d4\u10e1\u10e2\u10d4\u10d1\u10d8 (U+E, LFTs, \u10db\u10d0\u10d7 \u10e8\u10dd\u10e0\u10d8\u10e1 AST)<\/strong>;<\/li>\n\n\n\n<li><strong>LDH<\/strong>;<\/li>\n\n\n\n<li><strong>\u10e2\u10e0\u10dd\u10de\u10dd\u10dc\u10d8\u10dc\u10d8, NT pro-BNP<\/strong>.<\/li>\n<\/ul>\n\n\n\n<p><strong>\u10d3\u10d0\u10db\u10d0\u10e2\u10d4\u10d1\u10d8\u10d7 \u10d2\u10d0\u10dc\u10e1\u10d0\u10ee\u10d8\u10da\u10d5\u10d4\u10da\u10d8 \u10d2\u10d0\u10db\u10dd\u10d9\u10d5\u10da\u10d4\u10d5\u10d4\u10d1\u10d8:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u10d8\u10dc\u10e4\u10d4\u10e5\u10ea\u10d8\u10d8\u10e1 \u10e1\u10d9\u10e0\u10d8\u10dc\u10d8\u10dc\u10d2\u10d8<\/strong>: \u10e1\u10d0\u10ed\u10d8\u10e0\u10dd\u10d0 \u10e8\u10d4\u10e1\u10d0\u10d1\u10d0\u10db\u10d8\u10e1\u10d8 \u10d0\u10dc\u10d0\u10da\u10d8\u10d6\u10d4\u10d1\u10d8, \u10e0\u10d0\u10d3\u10d2\u10d0\u10dc MAS-\u10d8\u10e1 \u10d3\u10d0 \u10e1\u10d4\u10e4\u10e1\u10d8\u10e1\u10d8\u10e1 \u10d9\u10da\u10d8\u10dc\u10d8\u10d9\u10e3\u10e0\u10d8 \u10dc\u10d8\u10e8\u10dc\u10d4\u10d1\u10d8 \u10d4\u10e0\u10d7\u10db\u10d0\u10dc\u10d4\u10d7\u10e1 \u10f0\u10d2\u10d0\u10d5\u10e1;<\/li>\n\n\n\n<li><strong>\u10eb\u10d5\u10da\u10d8\u10e1 \u10e2\u10d5\u10d8\u10dc\u10d8\u10e1 \u10d0\u10e1\u10de\u10d8\u10e0\u10d0\u10ea\u10d8\u10d0<\/strong>: \u10d7\u10e3\u10db\u10ea\u10d0, \u10dc\u10dd\u10e0\u10db\u10d0\u10da\u10e3\u10e0\u10d8 \u10e8\u10d4\u10d3\u10d4\u10d2\u10d8 MAS-\u10e1 \u10d0\u10e0 \u10d2\u10d0\u10db\u10dd\u10e0\u10d8\u10ea\u10ee\u10d0\u10d5\u10e1;<\/li>\n\n\n\n<li><strong>\u10de\u10d8\u10e0\u10d5\u10d4\u10da\u10d0\u10d3\u10d8 HLH-\u10d8\u10e1 \u10e1\u10d9\u10e0\u10d8\u10dc\u10d8\u10dc\u10d2\u10d8<\/strong>: \u10de\u10d4\u10e0\u10e4\u10dd\u10e0\u10d8\u10dc\u10d8, \u10d2\u10e0\u10d0\u10dc\u10e3\u10da\u10d4\u10d1\u10d8\u10e1 \u10d2\u10d0\u10db\u10dd\u10d7\u10d0\u10d5\u10d8\u10e1\u10e3\u10e4\u10da\u10d4\u10d1\u10d8\u10e1 \u10e2\u10d4\u10e1\u10e2\u10d8 (GRA), \u10d3\u10d0 SAP\/XIAP \u10db\u10d0\u10db\u10d0\u10d9\u10d0\u10ea\u10d4\u10d1\u10e8\u10d8 (\u10d8\u10ee\u10d8\u10da\u10d4\u10d7 \u10e5\u10d5\u10d4\u10db\u10dd\u10d7).<\/li>\n<\/ul>\n\n\n\n<p><strong>\u10d2\u10d0\u10db\u10dd\u10e5\u10d5\u10d4\u10e7\u10dc\u10d4\u10d1\u10e3\u10da\u10d8 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10e1\u10e2\u10d8\u10d9\u10e3\u10e0\u10d8 \u10d3\u10d0 \u10d9\u10da\u10d0\u10e1\u10d8\u10e4\u10d8\u10d9\u10d0\u10ea\u10d8\u10d8\u10e1 \u10d9\u10e0\u10d8\u10e2\u10d4\u10e0\u10d8\u10e3\u10db\u10d4\u10d1\u10d8<\/strong><\/p>\n\n\n\n<p>MAS-\u10d8\u10e1 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10d6\u10d8\u10e1 \u10d3\u10d0\u10e1\u10d0\u10d3\u10d2\u10d4\u10dc\u10d0\u10d3 <strong>SoJIA<\/strong>-\u10e1\u10d0 \u10d3\u10d0 <strong>SLE<\/strong>-\u10e1 \u10d9\u10dd\u10dc\u10e2\u10d4\u10e5\u10e1\u10e2\u10e8\u10d8 \u10d2\u10d0\u10db\u10dd\u10e7\u10d4\u10dc\u10d4\u10d1\u10e3\u10da\u10d8 \u10d9\u10e0\u10d8\u10e2\u10d4\u10e0\u10d8\u10e3\u10db\u10d4\u10d1\u10d8 \u10db\u10dd\u10ea\u10d4\u10db\u10e3\u10da\u10d8\u10d0 \u10e5\u10d5\u10d4\u10db\u10dd\u10d7. \u10d4\u10e1 \u10d9\u10e0\u10d8\u10e2\u10d4\u10e0\u10d8\u10e3\u10db\u10d4\u10d1\u10d8 \u10eb\u10d8\u10e0\u10d8\u10d7\u10d0\u10d3\u10d0\u10d3 \u10d9\u10d5\u10da\u10d4\u10d5\u10d4\u10d1\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1\u10d0\u10d0 \u10e8\u10d4\u10db\u10e3\u10e8\u10d0\u10d5\u10d4\u10d1\u10e3\u10da\u10d8, \u10db\u10d0\u10d2\u10e0\u10d0\u10db \u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0 \u10e1\u10d0\u10e1\u10d0\u10e0\u10d2\u10d4\u10d1\u10da\u10dd \u10d8\u10e7\u10dd\u10e1 \u10d9\u10da\u10d8\u10dc\u10d8\u10d9\u10e3\u10e0\u10d8 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10e1\u10e2\u10d8\u10d9\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1. \u10d7\u10e3\u10db\u10ea\u10d0, \u10d9\u10dd\u10dc\u10d9\u10e0\u10d4\u10e2\u10e3\u10da\u10d8 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10e1\u10e2\u10d8\u10d9\u10e3\u10e0\u10d8 \u10d6\u10e6\u10d5\u10d0\u10e0\u10d8\u10e1 \u10db\u10d8\u10e6\u10ec\u10d4\u10d5\u10d0 \u10d9\u10da\u10d8\u10dc\u10d8\u10d9\u10e3\u10e0\u10d0\u10d3 \u10dc\u10d0\u10d9\u10da\u10d4\u10d1\u10d0\u10d3 \u10db\u10dc\u10d8\u10e8\u10d5\u10dc\u10d4\u10da\u10dd\u10d5\u10d0\u10dc\u10d8\u10d0 \u10d3\u10d0 \u10e2\u10d4\u10dc\u10d3\u10d4\u10dc\u10ea\u10d8\u10d4\u10d1\u10d8\u10e1 \u10db\u10dd\u10dc\u10d8\u10e2\u10dd\u10e0\u10d8\u10dc\u10d2\u10d8 \u10e3\u10e4\u10e0\u10dd \u10d4\u10e4\u10d4\u10e5\u10e2\u10e3\u10e0\u10d8 \u10db\u10d4\u10d7\u10dd\u10d3\u10d8\u10d0.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>PRINTO\/EULAR 2016 \u10d9\u10da\u10d0\u10e1\u10d8\u10e4\u10d8\u10d9\u10d0\u10ea\u10d8\u10d8\u10e1 \u10d9\u10e0\u10d8\u10e2\u10d4\u10e0\u10d8\u10e3\u10db\u10d4\u10d1\u10d8 MAS-\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1 SoJIA-\u10e1 \u10d9\u10dd\u10dc\u10e2\u10d4\u10e5\u10e1\u10e2\u10e8\u10d8<\/strong><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u10de\u10d8\u10e0\u10d5\u10d4\u10da\u10d0\u10d3\u10d8 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10e1\u10e2\u10d8\u10d9\u10e3\u10e0\u10d8 \u10e1\u10d0\u10ee\u10d4\u10da\u10db\u10eb\u10e6\u10d5\u10d0\u10dc\u10d4\u10da\u10dd MAS-\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1 SoJIA-\u10e1 \u10d3\u10e0\u10dd\u10e1 (11):<\/strong><\/h4>\n\n\n\n<p>\u10ea\u10ee\u10d4\u10da\u10d4\u10d1\u10d8\u10d0\u10dc\u10d8 \u10de\u10d0\u10ea\u10d8\u10d4\u10dc\u10e2\u10d8, \u10e0\u10dd\u10db\u10d4\u10da\u10e1\u10d0\u10ea \u10d0\u10e5\u10d5\u10e1 \u10d3\u10d0\u10d3\u10d0\u10e1\u10e2\u10e3\u10e0\u10d4\u10d1\u10e3\u10da\u10d8 SoJIA \u10d3\u10d0:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u10e4\u10d4\u10e0\u10d8\u10e2\u10d8\u10dc\u10d8 &gt;684 ng\/ml<\/strong><\/li>\n\n\n\n<li>\u10d3\u10d0 \u10e5\u10d5\u10d4\u10db\u10dd\u10d7 \u10db\u10dd\u10ea\u10d4\u10db\u10e3\u10da\u10d8 \u10d9\u10e0\u10d8\u10e2\u10d4\u10e0\u10d8\u10e3\u10db\u10d4\u10d1\u10d8\u10d3\u10d0\u10dc \u10dc\u10d4\u10d1\u10d8\u10e1\u10db\u10d8\u10d4\u10e0\u10d8 2:\n<ul class=\"wp-block-list\">\n<li>\u10d7\u10e0\u10dd\u10db\u10d1\u10dd\u10ea\u10d8\u10e2\u10d4\u10d1\u10d8\u10e1 \u10e0\u10d0\u10dd\u10d3\u10d4\u10dc\u10dd\u10d1\u10d0 \u2264181 \u00d7 10\u2079\/\u10da\u10d8\u10e2\u10e0\u10d6\u10d4;<\/li>\n\n\n\n<li>\u10d0\u10e1\u10de\u10d0\u10e0\u10e2\u10d0\u10e2\u10d0\u10db\u10d8\u10dc\u10dd\u10e2\u10e0\u10d0\u10dc\u10e1\u10e4\u10d4\u10e0\u10d0\u10d6\u10d0 (AST) &gt;48 \u10d4\u10e0\u10d7\u10d4\u10e3\u10da\u10d8\/\u10da\u10d8\u10e2\u10e0\u10d6\u10d4;<\/li>\n\n\n\n<li>\u10e2\u10e0\u10d8\u10d2\u10da\u10d8\u10ea\u10d4\u10e0\u10d8\u10d3\u10d4\u10d1\u10d8 &gt;156 \u10db\u10d2\/\u10d3\u10da;<\/li>\n\n\n\n<li>\u10e4\u10d8\u10d1\u10e0\u10d8\u10dc\u10dd\u10d2\u10d4\u10dc\u10d8 \u2264360 \u10db\u10d2\/\u10d3\u10da.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u10da\u10d0\u10d1\u10dd\u10e0\u10d0\u10e2\u10dd\u10e0\u10d8\u10e3\u10da\u10d8 \u10d9\u10e0\u10d8\u10e2\u10d4\u10e0\u10d8\u10e3\u10db\u10d4\u10d1\u10d8:<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u10d7\u10e0\u10dd\u10db\u10d1\u10dd\u10ea\u10d8\u10e2\u10d4\u10d1\u10d8\u10e1 \u10e8\u10d4\u10db\u10ea\u10d8\u10e0\u10d4\u10d1\u10e3\u10da\u10d8 \u10e0\u10d0\u10dd\u10d3\u10d4\u10dc\u10dd\u10d1\u10d0 \u2264262 \u00d7 10\u2079\/\u10da;<\/li>\n\n\n\n<li>\u10d0\u10e1\u10de\u10d0\u10e0\u10e2\u10d0\u10e2\u10d0\u10db\u10d8\u10dc\u10dd\u10e2\u10e0\u10d0\u10dc\u10e1\u10e4\u10d4\u10e0\u10d0\u10d6\u10d8\u10e1 \u10db\u10dd\u10db\u10d0\u10e2\u10d4\u10d1\u10e3\u10da\u10d8 \u10d3\u10dd\u10dc\u10d4 &gt;59 \u10d4\u10e0\u10d7\u10d4\u10e3\u10da\u10d8\/\u10da;<\/li>\n\n\n\n<li>\u10da\u10d4\u10d8\u10d9\u10dd\u10ea\u10d8\u10e2\u10d4\u10d1\u10d8\u10e1 \u10e8\u10d4\u10db\u10ea\u10d8\u10e0\u10d4\u10d1\u10e3\u10da\u10d8 \u10e0\u10d0\u10dd\u10d3\u10d4\u10dc\u10dd\u10d1\u10d0 \u22644.0 \u00d7 10\u2079\/\u10da;<\/li>\n\n\n\n<li>\u10f0\u10d8\u10de\u10dd\u10e4\u10d8\u10d1\u10e0\u10d8\u10dc\u10dd\u10d2\u10d4\u10dc\u10d4\u10db\u10d8\u10d0 \u22642.5 \u10d2\/\u10da.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u10d9\u10da\u10d8\u10dc\u10d8\u10d9\u10e3\u10e0\u10d8 \u10d9\u10e0\u10d8\u10e2\u10d4\u10e0\u10d8\u10e3\u10db\u10d4\u10d1\u10d8:<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u10ea\u10d4\u10dc\u10e2\u10e0\u10d0\u10da\u10e3\u10e0\u10d8 \u10dc\u10d4\u10e0\u10d5\u10e3\u10da\u10d8 \u10e1\u10d8\u10e1\u10e2\u10d4\u10db\u10d8\u10e1 \u10d3\u10d8\u10e1\u10e4\u10e3\u10dc\u10e5\u10ea\u10d8\u10d0: \u10d2\u10d0\u10e6\u10d8\u10d6\u10d8\u10d0\u10dc\u10d4\u10d1\u10d0, \u10d3\u10d4\u10d6\u10dd\u10e0\u10d8\u10d4\u10dc\u10e2\u10d0\u10ea\u10d8\u10d0, \u10da\u10d4\u10d7\u10d0\u10e0\u10d2\u10d8\u10d0, \u10d7\u10d0\u10d5\u10d8\u10e1 \u10e2\u10d9\u10d8\u10d5\u10d8\u10da\u10d8, \u10d9\u10e0\u10e3\u10dc\u10e9\u10ee\u10d5\u10d4\u10d1\u10d8, \u10d9\u10dd\u10db\u10d0;<\/li>\n\n\n\n<li>\u10f0\u10d4\u10db\u10dd\u10e0\u10d0\u10d2\u10d8\u10d4\u10d1\u10d8: \u10de\u10e3\u10e0\u10de\u10e3\u10e0\u10d0, \u10db\u10d0\u10e0\u10e2\u10d8\u10d5\u10d0\u10d3 \u10d2\u10d0\u10e9\u10d4\u10dc\u10d8\u10da\u10d8 \u10e1\u10d8\u10e1\u10ee\u10da\u10e9\u10d0\u10e5\u10ea\u10d4\u10d5\u10d4\u10d1\u10d8, \u10da\u10dd\u10e0\u10ec\u10dd\u10d5\u10d0\u10dc\u10d4\u10d1\u10d8\u10e1 \u10e1\u10d8\u10e1\u10ee\u10da\u10d3\u10d4\u10dc\u10d0;<\/li>\n\n\n\n<li>\u10f0\u10d4\u10de\u10d0\u10e2\u10dd\u10db\u10d4\u10d2\u10d0\u10da\u10d8\u10d0 \u22653 \u10e1\u10db \u10dc\u10d4\u10d9\u10dc\u10d7\u10d0 \u10e0\u10d9\u10d0\u10da\u10d8\u10d3\u10d0\u10dc.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u10f0\u10d8\u10e1\u10e2\u10dd\u10de\u10d0\u10d7\u10dd\u10da\u10dd\u10d2\u10d8\u10e3\u10e0\u10d8 \u10d9\u10e0\u10d8\u10e2\u10d4\u10e0\u10d8\u10e3\u10db\u10d8:<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u10db\u10d0\u10d9\u10e0\u10dd\u10e4\u10d0\u10d2\u10d4\u10d1\u10d8\u10e1 \u10f0\u10d4\u10db\u10dd\u10e4\u10d0\u10d2\u10dd\u10ea\u10d8\u10e2\u10dd\u10d6\u10d8\u10e1 \u10d0\u10e0\u10e1\u10d4\u10d1\u10dd\u10d1\u10d0 \u10eb\u10d5\u10da\u10d8\u10e1 \u10e2\u10d5\u10d8\u10dc\u10d8\u10e1 \u10d0\u10e1\u10de\u10d8\u10e0\u10d0\u10e2\u10e8\u10d8 (\u10e1\u10d0\u10ed\u10d8\u10e0\u10dd\u10d0 \u10db\u10ee\u10dd\u10da\u10dd\u10d3 \u10e1\u10d0\u10d4\u10ed\u10d5\u10dd \u10e8\u10d4\u10db\u10d7\u10ee\u10d5\u10d4\u10d5\u10d4\u10d1\u10e8\u10d8).<\/li>\n<\/ul>\n\n\n\n<p><strong>MAS-\u10d8\u10e1 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10d6\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1 \u10e1\u10d0\u10ed\u10d8\u10e0\u10dd\u10d0:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u10da\u10d0\u10d1\u10dd\u10e0\u10d0\u10e2\u10dd\u10e0\u10d8\u10e3\u10da\u10d8 \u10d9\u10e0\u10d8\u10e2\u10d4\u10e0\u10d8\u10e3\u10db\u10d4\u10d1\u10d8\u10d3\u10d0\u10dc 2 \u10d0\u10dc \u10db\u10d4\u10e2\u10d8,<\/li>\n\n\n\n<li>\u10d0\u10dc 2-3 \u10d9\u10da\u10d8\u10dc\u10d8\u10d9\u10e3\u10e0\u10d8 \u10d3\u10d0\/\u10d0\u10dc \u10da\u10d0\u10d1\u10dd\u10e0\u10d0\u10e2\u10dd\u10e0\u10d8\u10e3\u10da\u10d8 \u10d9\u10e0\u10d8\u10e2\u10d4\u10e0\u10d8\u10e3\u10db\u10d8.<\/li>\n<\/ul>\n\n\n\n<p><strong>\u10e8\u10d4\u10dc\u10d8\u10e8\u10d5\u10dc\u10d4\u10d1\u10d8:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u10da\u10d0\u10d1\u10dd\u10e0\u10d0\u10e2\u10dd\u10e0\u10d8\u10e3\u10da\u10d8 \u10d9\u10e0\u10d8\u10e2\u10d4\u10e0\u10d8\u10e3\u10db\u10d4\u10d1\u10d8\u10e1 \u10d6\u10e6\u10d5\u10e0\u10d4\u10d1\u10d8 \u10db\u10ee\u10dd\u10da\u10dd\u10d3 \u10db\u10d0\u10d2\u10d0\u10da\u10d8\u10d7\u10d8\u10e1 \u10e1\u10d0\u10ee\u10d8\u10d7\u10d0\u10d0 \u10ec\u10d0\u10e0\u10db\u10dd\u10d3\u10d2\u10d4\u10dc\u10d8\u10da\u10d8;<\/li>\n\n\n\n<li>\u10d9\u10da\u10d8\u10dc\u10d8\u10d9\u10e3\u10e0\u10d8 \u10d9\u10e0\u10d8\u10e2\u10d4\u10e0\u10d8\u10e3\u10db\u10d4\u10d1\u10d8 \u10e3\u10e4\u10e0\u10dd \u10e1\u10d0\u10e1\u10d0\u10e0\u10d2\u10d4\u10d1\u10da\u10dd\u10d0 \u10d9\u10da\u10d0\u10e1\u10d8\u10e4\u10d8\u10d9\u10d0\u10ea\u10d8\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1, \u10d5\u10d8\u10d3\u10e0\u10d4 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10e1\u10e2\u10d8\u10d9\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1, \u10e0\u10d0\u10d3\u10d2\u10d0\u10dc \u10d8\u10e1\u10d8\u10dc\u10d8 \u10ee\u10e8\u10d8\u10e0\u10d0\u10d3 \u10d2\u10d5\u10d8\u10d0\u10dc \u10d2\u10d0\u10db\u10dd\u10d5\u10da\u10d8\u10dc\u10d3\u10d4\u10d1\u10d0 MAS-\u10d8\u10e1 \u10db\u10d8\u10db\u10d3\u10d8\u10dc\u10d0\u10e0\u10d4\u10dd\u10d1\u10d8\u10e1\u10d0\u10e1 \u10d3\u10d0 \u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0 \u10d0\u10d3\u10e0\u10d4 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10d6\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1 \u10e8\u10d4\u10d6\u10e6\u10e3\u10d3\u10e3\u10da\u10d8 \u10e6\u10d8\u10e0\u10d4\u10d1\u10e3\u10da\u10d4\u10d1\u10d0 \u10f0\u10e5\u10dd\u10dc\u10d3\u10d4\u10e1.<\/li>\n\n\n\n<li>SoJIA-\u10e1\u10d7\u10d0\u10dc \u10d0\u10e1\u10dd\u10ea\u10d8\u10e0\u10d4\u10d1\u10e3\u10da MAS-\u10e8\u10d8 \u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0 \u10d2\u10d0\u10db\u10dd\u10d5\u10da\u10d8\u10dc\u10d3\u10d4\u10e1: <strong>\u10e3\u10ec\u10e7\u10d5\u10d4\u10e2\u10d8 \u10db\u10d0\u10e6\u10d0\u10da\u10d8 \u10e1\u10d8\u10ea\u10ee\u10d4<\/strong>, \u10e1\u10de\u10da\u10d4\u10dc\u10dd\u10db\u10d4\u10d2\u10d0\u10da\u10d8\u10d0, \u10d2\u10d4\u10dc\u10d4\u10e0\u10d0\u10da\u10d8\u10d6\u10d4\u10d1\u10e3\u10da\u10d8 \u10da\u10d8\u10db\u10e4\u10d0\u10d3\u10d4\u10dc\u10dd\u10de\u10d0\u10d7\u10d8\u10d0 \u10d3\u10d0 \u10d0\u10e0\u10d7\u10e0\u10d8\u10e2\u10d8\u10e1 \u10dc\u10d8\u10e8\u10dc\u10d4\u10d1\u10d8\u10e1 \u10d3\u10d0 \u10e1\u10d8\u10db\u10de\u10e2\u10dd\u10db\u10d4\u10d1\u10d8\u10e1 \u10de\u10d0\u10e0\u10d0\u10d3\u10dd\u10e5\u10e1\u10e3\u10da\u10d8 \u10d2\u10d0\u10e3\u10db\u10ef\u10dd\u10d1\u10d4\u10e1\u10d4\u10d1\u10d0.<\/li>\n\n\n\n<li>\u10e1\u10ee\u10d5\u10d0 \u10da\u10d0\u10d1\u10dd\u10e0\u10d0\u10e2\u10dd\u10e0\u10d8\u10e3\u10da\u10d8 \u10d0\u10dc\u10dd\u10db\u10d0\u10da\u10d8\u10d4\u10d1\u10d8 \u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0 \u10db\u10dd\u10d8\u10ea\u10d0\u10d5\u10d3\u10d4\u10e1: \u10d0\u10dc\u10d4\u10db\u10d8\u10d0\u10e1, \u10d4\u10e0\u10d8\u10d7\u10e0\u10dd\u10ea\u10d8\u10e2\u10d4\u10d1\u10d8\u10e1 \u10d3\u10d0\u10ea\u10d4\u10db\u10d8\u10e1 \u10e1\u10d8\u10e9\u10e5\u10d0\u10e0\u10d8\u10e1 \u10e8\u10d4\u10db\u10ea\u10d8\u10e0\u10d4\u10d1\u10d0\u10e1, ALT-\u10d8\u10e1 \u10db\u10dd\u10db\u10d0\u10e2\u10d4\u10d1\u10d0\u10e1, \u10d1\u10d8\u10da\u10d8\u10e0\u10e3\u10d1\u10d8\u10dc\u10d8\u10e1 \u10db\u10dd\u10db\u10d0\u10e2\u10d4\u10d1\u10d0\u10e1, \u10e4\u10d8\u10d1\u10e0\u10d8\u10dc\u10d8\u10e1 \u10d3\u10d4\u10d2\u10e0\u10d0\u10d3\u10d0\u10ea\u10d8\u10d8\u10e1 \u10de\u10e0\u10dd\u10d3\u10e3\u10e5\u10e2\u10d4\u10d1\u10d8\u10e1 \u10d0\u10e0\u10e1\u10d4\u10d1\u10dd\u10d1\u10d0\u10e1, LDH-\u10d8\u10e1 \u10db\u10dd\u10db\u10d0\u10e2\u10d4\u10d1\u10d0\u10e1, \u10f0\u10d8\u10de\u10d4\u10e0\u10e2\u10e0\u10d8\u10d2\u10da\u10d8\u10ea\u10d4\u10e0\u10d8\u10d3\u10d4\u10db\u10d8\u10d0\u10e1, \u10dc\u10d0\u10e2\u10e0\u10d8\u10e3\u10db\u10d8\u10e1 \u10d3\u10d0\u10d1\u10d0\u10da \u10d3\u10dd\u10dc\u10d4\u10e1, \u10d0\u10da\u10d1\u10e3\u10db\u10d8\u10dc\u10d8\u10e1 \u10e8\u10d4\u10db\u10ea\u10d8\u10e0\u10d4\u10d1\u10d0\u10e1 \u10d3\u10d0 \u10f0\u10d8\u10de\u10d4\u10e0\u10e4\u10d4\u10e0\u10d8\u10e2\u10d8\u10dc\u10d4\u10db\u10d8\u10d0\u10e1.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u10de\u10d8\u10e0\u10d5\u10d4\u10da\u10d0\u10d3\u10d8 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10e1\u10e2\u10d8\u10d9\u10e3\u10e0\u10d8 \u10e1\u10d0\u10ee\u10d4\u10da\u10db\u10eb\u10e6\u10d5\u10d0\u10dc\u10d4\u10da\u10dd MAS-\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1 \u10d8\u10e3\u10d5\u10d4\u10dc\u10d8\u10da\u10e3\u10e0\u10d8 SLE-\u10d8\u10e1 \u10d3\u10e0\u10dd\u10e1 (12):<\/strong><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u10d9\u10da\u10d8\u10dc\u10d8\u10d9\u10e3\u10e0\u10d8 \u10d9\u10e0\u10d8\u10e2\u10d4\u10e0\u10d8\u10e3\u10db\u10d4\u10d1\u10d8:<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u10ea\u10ee\u10d4\u10da\u10d4\u10d1\u10d0 (&gt;38\u00b0C);<\/li>\n\n\n\n<li>\u10f0\u10d4\u10de\u10d0\u10e2\u10dd\u10db\u10d4\u10d2\u10d0\u10da\u10d8\u10d0 (\u22653 \u10e1\u10db \u10dc\u10d4\u10d9\u10dc\u10d7\u10d0 \u10e0\u10d9\u10d0\u10da\u10d8\u10d3\u10d0\u10dc);<\/li>\n\n\n\n<li>\u10e1\u10de\u10da\u10d4\u10dc\u10dd\u10db\u10d4\u10d2\u10d0\u10da\u10d8\u10d0 (\u22653 \u10e1\u10db \u10dc\u10d4\u10d9\u10dc\u10d7\u10d0 \u10e0\u10d9\u10d0\u10da\u10d8\u10d3\u10d0\u10dc);<\/li>\n\n\n\n<li>\u10f0\u10d4\u10db\u10dd\u10e0\u10d0\u10d2\u10d8\u10e3\u10da\u10d8 \u10db\u10d0\u10dc\u10d8\u10e4\u10d4\u10e1\u10e2\u10d0\u10ea\u10d8\u10d4\u10d1\u10d8 (\u10de\u10e3\u10e0\u10de\u10e3\u10e0\u10d0, \u10db\u10d0\u10e0\u10e2\u10d8\u10d5\u10d8 \u10e1\u10d8\u10e1\u10ee\u10da\u10e9\u10d0\u10e5\u10ea\u10d4\u10d5\u10d4\u10d1\u10d8 \u10d0\u10dc \u10da\u10dd\u10e0\u10ec\u10dd\u10d5\u10d0\u10dc\u10d4\u10d1\u10d8\u10e1 \u10e1\u10d8\u10e1\u10ee\u10da\u10d3\u10d4\u10dc\u10d0).<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u10da\u10d0\u10d1\u10dd\u10e0\u10d0\u10e2\u10dd\u10e0\u10d8\u10e3\u10da\u10d8 \u10d9\u10e0\u10d8\u10e2\u10d4\u10e0\u10d8\u10e3\u10db\u10d4\u10d1\u10d8:<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u10ea\u10d4\u10dc\u10e2\u10e0\u10d0\u10da\u10e3\u10e0\u10d8 \u10dc\u10d4\u10e0\u10d5\u10e3\u10da\u10d8 \u10e1\u10d8\u10e1\u10e2\u10d4\u10db\u10d8\u10e1 \u10d3\u10d8\u10e1\u10e4\u10e3\u10dc\u10e5\u10ea\u10d8\u10d0 (\u10d2\u10d0\u10e6\u10d8\u10d6\u10d8\u10d0\u10dc\u10d4\u10d1\u10d0, \u10d3\u10d4\u10d6\u10dd\u10e0\u10d8\u10d4\u10dc\u10e2\u10d0\u10ea\u10d8\u10d0, \u10da\u10d4\u10d7\u10d0\u10e0\u10d2\u10d8\u10d0, \u10d7\u10d0\u10d5\u10d8\u10e1 \u10e2\u10d9\u10d8\u10d5\u10d8\u10da\u10d8, \u10d9\u10e0\u10e3\u10dc\u10e9\u10ee\u10d5\u10d4\u10d1\u10d8 \u10d0\u10dc \u10d9\u10dd\u10db\u10d0);<\/li>\n\n\n\n<li>\u10ea\u10d8\u10e2\u10dd\u10de\u10d4\u10dc\u10d8\u10d0, \u10e0\u10dd\u10db\u10d4\u10da\u10d8\u10ea \u10d2\u10d0\u10d5\u10da\u10d4\u10dc\u10d0\u10e1 \u10d0\u10ee\u10d3\u10d4\u10dc\u10e1 2 \u10d0\u10dc \u10db\u10d4\u10e2 \u10e3\u10ef\u10e0\u10d4\u10d3\u10e3\u10da \u10ee\u10d0\u10d6\u10d6\u10d4 (\u10da\u10d4\u10d8\u10d9\u10dd\u10ea\u10d8\u10e2\u10d4\u10d1\u10d8\u10e1 \u10e0\u10d0\u10dd\u10d3\u10d4\u10dc\u10dd\u10d1\u10d0 \u22644.0 \u00d7 10\u2079\/\u10da, \u10f0\u10d4\u10db\u10dd\u10d2\u10da\u10dd\u10d1\u10d8\u10dc\u10d8 \u226490 \u10d2\/\u10da \u10d0\u10dc \u10d7\u10e0\u10dd\u10db\u10d1\u10dd\u10ea\u10d8\u10e2\u10d4\u10d1\u10d8\u10e1 \u10e0\u10d0\u10dd\u10d3\u10d4\u10dc\u10dd\u10d1\u10d0 \u2264150 \u00d7 10\u2079\/\u10da);<\/li>\n\n\n\n<li>\u10d0\u10e1\u10de\u10d0\u10e0\u10e2\u10d0\u10e2\u10d0\u10db\u10d8\u10dc\u10dd\u10e2\u10e0\u10d0\u10dc\u10e1\u10e4\u10d4\u10e0\u10d0\u10d6\u10d8\u10e1 \u10db\u10dd\u10db\u10d0\u10e2\u10d4\u10d1\u10d0 (&gt;40 \u10d4\u10e0\u10d7\u10d4\u10e3\u10da\u10d8\/\u10da);<\/li>\n\n\n\n<li>\u10da\u10d0\u10e5\u10e2\u10d0\u10e2\u10d3\u10d4\u10f0\u10d8\u10d3\u10e0\u10dd\u10d2\u10d4\u10dc\u10d0\u10d6\u10d8\u10e1 \u10db\u10dd\u10db\u10d0\u10e2\u10d4\u10d1\u10d0 (&gt;567 \u10d4\u10e0\u10d7\u10d4\u10e3\u10da\u10d8\/\u10da);<\/li>\n\n\n\n<li>\u10f0\u10d8\u10de\u10dd\u10e4\u10d8\u10d1\u10e0\u10d8\u10dc\u10dd\u10d2\u10d4\u10dc\u10d4\u10db\u10d8\u10d0 (\u10e4\u10d8\u10d1\u10e0\u10d8\u10dc\u10dd\u10d2\u10d4\u10dc\u10d8 \u22641.5 \u10d2\/\u10da);<\/li>\n\n\n\n<li>\u10f0\u10d8\u10de\u10d4\u10e0\u10e2\u10e0\u10d8\u10d2\u10da\u10d8\u10ea\u10d4\u10e0\u10d8\u10d3\u10d4\u10db\u10d8\u10d0 (&gt;178 \u10db\u10d2\/\u10d3\u10da);<\/li>\n\n\n\n<li>\u10f0\u10d8\u10de\u10d4\u10e0\u10e4\u10d4\u10e0\u10d8\u10e2\u10d8\u10dc\u10d4\u10db\u10d8\u10d0 (&gt;500 \u03bcg\/\u10da).<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u10f0\u10d8\u10e1\u10e2\u10dd\u10de\u10d0\u10d7\u10dd\u10da\u10dd\u10d2\u10d8\u10e3\u10e0\u10d8 \u10d9\u10e0\u10d8\u10e2\u10d4\u10e0\u10d8\u10e3\u10db\u10d8:<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u10db\u10d0\u10d9\u10e0\u10dd\u10e4\u10d0\u10d2\u10d4\u10d1\u10d8\u10e1 \u10f0\u10d4\u10db\u10dd\u10e4\u10d0\u10d2\u10dd\u10ea\u10d8\u10e2\u10dd\u10d6\u10d8\u10e1 \u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d4\u10d1\u10d0 \u10eb\u10d5\u10da\u10d8\u10e1 \u10e2\u10d5\u10d8\u10dc\u10d8\u10e1 \u10d0\u10e1\u10de\u10d8\u10e0\u10d0\u10e2\u10e8\u10d8 (\u10e1\u10d0\u10ed\u10d8\u10e0\u10dd\u10d0 \u10db\u10ee\u10dd\u10da\u10dd\u10d3 \u10e1\u10d0\u10d4\u10ed\u10d5\u10dd \u10e8\u10d4\u10db\u10d7\u10ee\u10d5\u10d4\u10d5\u10d4\u10d1\u10e8\u10d8).<\/li>\n<\/ul>\n\n\n\n<p><strong>MAS-\u10d8\u10e1 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10d6\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1 \u10e1\u10d0\u10ed\u10d8\u10e0\u10dd\u10d0:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u10db\u10d8\u10dc\u10d8\u10db\u10e3\u10db 1 \u10d9\u10da\u10d8\u10dc\u10d8\u10d9\u10e3\u10e0\u10d8 \u10d9\u10e0\u10d8\u10e2\u10d4\u10e0\u10d8\u10e3\u10db\u10d8 \u10d3\u10d0 2 \u10d0\u10dc \u10db\u10d4\u10e2\u10d8 \u10da\u10d0\u10d1\u10dd\u10e0\u10d0\u10e2\u10dd\u10e0\u10d8\u10e3\u10da\u10d8 \u10d9\u10e0\u10d8\u10e2\u10d4\u10e0\u10d8\u10e3\u10db\u10d8.<\/li>\n<\/ul>\n\n\n\n<p><strong>\u10e8\u10d4\u10dc\u10d8\u10e8\u10d5\u10dc\u10d4\u10d1\u10d8:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u10d4\u10e1 \u10d9\u10e0\u10d8\u10e2\u10d4\u10e0\u10d8\u10e3\u10db\u10d4\u10d1\u10d8 \u10e8\u10d4\u10db\u10e3\u10e8\u10d0\u10d5\u10d4\u10d1\u10e3\u10da\u10d8\u10d0 \u10d0\u10e5\u10e2\u10d8\u10e3\u10e0\u10d8 \u10d8\u10e3\u10d5\u10d4\u10dc\u10d8\u10da\u10e3\u10e0\u10d8 \u10e1\u10d8\u10e1\u10e2\u10d4\u10db\u10e3\u10e0\u10d8 \u10ec\u10d8\u10d7\u10d4\u10da\u10d8 \u10db\u10d2\u10da\u10e3\u10e0\u10d0\u10e1 (SLE) \u10db\u10e5\u10dd\u10dc\u10d4 \u10de\u10d0\u10ea\u10d8\u10d4\u10dc\u10e2\u10d4\u10d1\u10d6\u10d4.<\/li>\n\n\n\n<li>MAS-\u10d8\u10e1 \u10d8\u10dc\u10e4\u10d4\u10e5\u10ea\u10d8\u10e3\u10e0\u10d8 \u10d2\u10d0\u10e0\u10d7\u10e3\u10da\u10d4\u10d1\u10d4\u10d1\u10d8\u10e1\u10d2\u10d0\u10dc \u10d3\u10d8\u10e4\u10d4\u10e0\u10d4\u10dc\u10ea\u10d8\u10e0\u10d4\u10d1\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1 \u10d9\u10e0\u10d8\u10e2\u10d4\u10e0\u10d8\u10e3\u10db\u10d4\u10d1\u10d8 \u10e8\u10d4\u10e1\u10d0\u10eb\u10da\u10dd\u10d0 \u10e1\u10d0\u10d9\u10db\u10d0\u10e0\u10d8\u10e1\u10d0\u10d3 \u10db\u10eb\u10da\u10d0\u10d5\u10e0\u10d8 \u10d0\u10e0 \u10d8\u10e7\u10dd\u10e1.<\/li>\n<\/ul>\n\n\n\n<p><strong>\u10e1\u10d0\u10ec\u10e7\u10d8\u10e1\u10d8 \u10db\u10d9\u10e3\u10e0\u10dc\u10d0\u10da\u10dd\u10d1\u10d0<\/strong><\/p>\n\n\n\n<p>MAS \u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0 \u10e4\u10d0\u10e2\u10d0\u10da\u10e3\u10e0\u10d8 \u10d8\u10e7\u10dd\u10e1, \u10d7\u10e3 \u10db\u10d9\u10e3\u10e0\u10dc\u10d0\u10da\u10dd\u10d1\u10d0 \u10d3\u10e0\u10dd\u10e3\u10da\u10d0\u10d3 \u10d0\u10e0 \u10d2\u10d0\u10dc\u10ee\u10dd\u10e0\u10ea\u10d8\u10d4\u10da\u10d3\u10d4\u10d1\u10d0. \u10d0\u10e3\u10ea\u10d8\u10da\u10d4\u10d1\u10d4\u10da\u10d8\u10d0 \u10e1\u10d0\u10e1\u10ec\u10e0\u10d0\u10e4\u10dd \u10d2\u10d0\u10db\u10dd\u10d9\u10d5\u10da\u10d4\u10d5\u10d4\u10d1\u10d8\u10e1\u10d0 \u10d3\u10d0 \u10db\u10d0\u10e0\u10d7\u10d5\u10d8\u10e1 \u10e9\u10d0\u10e2\u10d0\u10e0\u10d4\u10d1\u10d0. \u10e7\u10d5\u10d4\u10da\u10d0 \u10d1\u10d0\u10d5\u10e8\u10d5\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1, \u10d5\u10d8\u10e1\u10d0\u10ea \u10d0\u10e5\u10d5\u10e1 \u10ea\u10ee\u10d4\u10da\u10d4\u10d1\u10d0 \u10d3\u10d0 \u10f0\u10d8\u10de\u10d4\u10e0\u10e4\u10d4\u10e0\u10d8\u10e2\u10d8\u10dc\u10d4\u10db\u10d8\u10d0, <strong>\u10e1\u10de\u10d4\u10ea\u10d8\u10d0\u10da\u10d8\u10e1\u10e2\u10d8\u10e1 \u10d9\u10dd\u10dc\u10e1\u10e3\u10da\u10e2\u10d0\u10ea\u10d8\u10d0 \u10e1\u10ec\u10e0\u10d0\u10e4\u10d0\u10d3 \u10e3\u10dc\u10d3\u10d0 \u10e9\u10d0\u10e2\u10d0\u10e0\u10d3\u10d4\u10e1<\/strong>. <strong>\u10d1\u10d0\u10d5\u10e8\u10d5\u10d7\u10d0 \u10e0\u10d4\u10d5\u10db\u10d0\u10e2\u10dd\u10da\u10dd\u10d2\u10e1<\/strong> \u10e3\u10dc\u10d3\u10d0 \u10db\u10d8\u10db\u10d0\u10e0\u10d7\u10dd\u10d7 \u10e7\u10d5\u10d4\u10da\u10d0 \u10d8\u10db \u10d1\u10d0\u10d5\u10e8\u10d5\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1, \u10e0\u10dd\u10db\u10da\u10d4\u10d1\u10e1\u10d0\u10ea \u10d0\u10e5\u10d5\u10d7 \u10e0\u10d4\u10d5\u10db\u10d0\u10e2\u10dd\u10da\u10dd\u10d2\u10d8\u10e3\u10e0\u10d8 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10d6\u10d8 \u10d3\u10d0 \u10db\u10d0\u10d7\u10d7\u10d0\u10dc \u10d2\u10d0\u10db\u10dd\u10d5\u10da\u10d8\u10dc\u10d3\u10d0 \u10ea\u10ee\u10d4\u10da\u10d4\u10d1\u10d0 \u10d3\u10d0 \u10f0\u10d8\u10de\u10d4\u10e0\u10e4\u10d4\u10e0\u10d8\u10e2\u10d8\u10dc\u10d4\u10db\u10d8\u10d0 (\u10d2\u10d0\u10dc\u10e1\u10d0\u10d9\u10e3\u10d7\u10e0\u10d4\u10d1\u10d8\u10d7, \u10d7\u10e3 \u10e4\u10d4\u10e0\u10d8\u10e2\u10d8\u10dc\u10d8\u10e1 \u10d3\u10dd\u10dc\u10d4 \u2265500 \u03bcg\/l).<\/p>\n\n\n\n<p>\u10db\u10d9\u10e3\u10e0\u10dc\u10d0\u10da\u10dd\u10d1\u10d0 \u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10e1\u10e2\u10d0\u10dc\u10d3\u10d0\u10e0\u10e2\u10d8\u10d6\u10d4\u10d1\u10e3\u10da\u10d8 \u10d3\u10d0 \u10e3\u10dc\u10d3\u10d0 \u10d8\u10e7\u10dd\u10e1 \u10db\u10d8\u10db\u10d0\u10e0\u10d7\u10e3\u10da\u10d8 \u10eb\u10d8\u10e0\u10d8\u10d7\u10d0\u10d3\u10d8 \u10d3\u10d0\u10d0\u10d5\u10d0\u10d3\u10d4\u10d1\u10d8\u10e1 \u10db\u10d0\u10e0\u10d7\u10d5\u10d0\u10d6\u10d4. \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10e1\u10e2\u10d8\u10d9\u10e3\u10e0\u10d8 \u10d2\u10d0\u10e3\u10e0\u10d9\u10d5\u10d4\u10d5\u10da\u10dd\u10d1\u10d8\u10e1 \u10e8\u10d4\u10db\u10d7\u10ee\u10d5\u10d4\u10d5\u10d0\u10e8\u10d8, \u10e8\u10d4\u10e1\u10d0\u10eb\u10da\u10dd\u10d0 \u10e1\u10d0\u10ed\u10d8\u10e0\u10dd \u10d2\u10d0\u10ee\u10d3\u10d4\u10e1 <strong>\u10eb\u10d5\u10da\u10d8\u10e1 \u10e2\u10d5\u10d8\u10dc\u10d8\u10e1 \u10d0\u10e1\u10de\u10d8\u10e0\u10d0\u10ea\u10d8\u10d0 (BMA)<\/strong> \u10db\u10d9\u10e3\u10e0\u10dc\u10d0\u10da\u10dd\u10d1\u10d8\u10e1 \u10d3\u10d0\u10ec\u10e7\u10d4\u10d1\u10d0\u10db\u10d3\u10d4, \u10e0\u10d0\u10ea \u10db\u10dd\u10d8\u10ea\u10d0\u10d5\u10e1 \u10db\u10e3\u10da\u10e2\u10d8\u10d3\u10d8\u10e1\u10ea\u10d8\u10de\u10da\u10d8\u10dc\u10e3\u10e0 \u10d2\u10d0\u10dc\u10ee\u10d8\u10da\u10d5\u10d0\u10e1 \u10e0\u10d4\u10d5\u10db\u10d0\u10e2\u10dd\u10da\u10dd\u10d2\u10d8\u10d8\u10e1, \u10f0\u10d4\u10db\u10d0\u10e2\u10dd\u10da\u10dd\u10d2\u10d8\u10d8\u10e1 \u10d3\u10d0 \u10ee\u10e8\u10d8\u10e0\u10d0\u10d3 \u10d8\u10dc\u10e4\u10d4\u10e5\u10ea\u10d8\u10e3\u10e0\u10d8 \u10d3\u10d0\u10d0\u10d5\u10d0\u10d3\u10d4\u10d1\u10d4\u10d1\u10d8\u10e1 \u10d2\u10e3\u10dc\u10d3\u10d4\u10d1\u10d7\u10d0\u10dc.<\/p>\n\n\n\n<p>\u10db\u10d9\u10e3\u10e0\u10dc\u10d0\u10da\u10dd\u10d1\u10d0 \u10e3\u10dc\u10d3\u10d0 \u10d3\u10d0\u10d8\u10ec\u10e7\u10dd\u10e1 \u10d1\u10d0\u10d5\u10e8\u10d5\u10d7\u10d0 \u10e0\u10d4\u10d5\u10db\u10d0\u10e2\u10dd\u10da\u10dd\u10d2\u10d8\u10e1 \u10e9\u10d0\u10e0\u10d7\u10e3\u10da\u10dd\u10d1\u10d8\u10d7 \u10d3\u10d0 \u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0 \u10db\u10dd\u10d8\u10ea\u10d0\u10d5\u10d3\u10d4\u10e1:<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u10e1\u10e2\u10d4\u10e0\u10dd\u10d8\u10d3\u10d4\u10d1\u10d8:<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u10e3\u10db\u10d4\u10e2\u10d4\u10e1 \u10de\u10d0\u10ea\u10d8\u10d4\u10dc\u10e2\u10e8\u10d8 MAS-\u10d8\u10e1 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10d6\u10d8\u10e1 \u10d3\u10e0\u10dd\u10e1 \u10e1\u10e2\u10d4\u10e0\u10dd\u10d8\u10d3\u10d7\u10d4\u10e0\u10d0\u10de\u10d8\u10d0 \u10e3\u10dc\u10d3\u10d0 \u10d3\u10d0\u10d8\u10ec\u10e7\u10dd\u10e1 \u10d3\u10e0\u10dd\u10e3\u10da\u10d0\u10d3, \u10e8\u10d4\u10e1\u10d0\u10d1\u10d0\u10db\u10d8\u10e1\u10d8 \u10d2\u10d0\u10db\u10dd\u10d9\u10d5\u10da\u10d4\u10d5\u10d4\u10d1\u10d8\u10e1 \u10e8\u10d4\u10db\u10d3\u10d4\u10d2;<\/li>\n\n\n\n<li>\u10d2\u10d0\u10db\u10dd\u10dc\u10d0\u10d9\u10da\u10d8\u10e1\u10d8 \u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0 \u10d8\u10e7\u10dd\u10e1 SoJIA-\u10d8\u10e1 \u10e8\u10d4\u10db\u10d7\u10ee\u10d5\u10d4\u10d5\u10d0\u10e8\u10d8, \u10e1\u10d0\u10d3\u10d0\u10ea \u10e8\u10d4\u10e1\u10d0\u10eb\u10da\u10d4\u10d1\u10d4\u10da\u10d8\u10d0 \u10db\u10dd\u10dc\u10dd\u10d7\u10d4\u10e0\u10d0\u10de\u10d8\u10d0 \u10d0\u10dc\u10d0\u10d9\u10d8\u10dc\u10e0\u10d0\u10d7\u10d8. \u10d4\u10e1 \u10d2\u10d0\u10d3\u10d0\u10ec\u10e7\u10d5\u10d4\u10e2\u10d8\u10da\u10d4\u10d1\u10d0 \u10e3\u10dc\u10d3\u10d0 \u10db\u10d8\u10d8\u10e6\u10dd\u10e1 \u10d2\u10d0\u10db\u10dd\u10ea\u10d3\u10d8\u10da\u10db\u10d0 \u10d1\u10d0\u10d5\u10e8\u10d5\u10d7\u10d0 \u10e0\u10d4\u10d5\u10db\u10d0\u10e2\u10dd\u10da\u10dd\u10d2\u10db\u10d0;<\/li>\n\n\n\n<li><strong>\u10d3\u10dd\u10d6\u10d0:<\/strong> 30 \u10db\u10d2\/\u10d9\u10d2\/\u10d3\u10e6\u10d4 \u10db\u10d4\u10d7\u10d8\u10da\u10de\u10e0\u10d4\u10d3\u10dc\u10d8\u10d6\u10dd\u10da\u10dd\u10dc\u10d8 IV \u10d2\u10d6\u10d8\u10d7 (\u10db\u10d0\u10e5\u10e1\u10d8\u10db\u10d0\u10da\u10e3\u10e0\u10d8 \u10d3\u10dd\u10d6\u10d0: 1 \u10d2\u10e0\u10d0\u10db\u10d8), \u10e0\u10dd\u10d2\u10dd\u10e0\u10ea \u10d4\u10e0\u10d7\u10ef\u10d4\u10e0\u10d0\u10d3\u10d8 \u10d8\u10dc\u10e4\u10e3\u10d6\u10d8\u10d0, 3 \u10d3\u10e6\u10d8\u10e1 \u10d2\u10d0\u10dc\u10db\u10d0\u10d5\u10da\u10dd\u10d1\u10d0\u10e8\u10d8;<\/li>\n\n\n\n<li>\u10e8\u10d4\u10db\u10d3\u10d2\u10dd\u10db\u10d8 \u10db\u10d0\u10e0\u10d7\u10d5\u10d0: 1-2 \u10db\u10d2\/\u10d9\u10d2\/\u10d3\u10e6\u10d4 \u10de\u10d4\u10e0\u10dd\u10e0\u10d0\u10da\u10e3\u10e0\u10d8 \u10de\u10e0\u10d4\u10d3\u10dc\u10d8\u10d6\u10dd\u10da\u10dd\u10dc\u10d8;<\/li>\n\n\n\n<li>\u10d2\u10d0\u10d7\u10d5\u10d0\u10da\u10d8\u10e1\u10ec\u10d8\u10dc\u10d4\u10d1\u10e3\u10da\u10d8 \u10e3\u10dc\u10d3\u10d0 \u10d8\u10e7\u10dd\u10e1 <strong>\u10d2\u10d0\u10e1\u10e2\u10e0\u10dd\u10de\u10e0\u10dd\u10e2\u10d4\u10e5\u10ea\u10d8\u10d0<\/strong> (\u10de\u10e0\u10dd\u10e2\u10dd\u10dc\u10e3\u10da\u10d8 \u10e2\u10e3\u10db\u10d1\u10dd\u10e1 \u10d8\u10dc\u10f0\u10d8\u10d1\u10d8\u10e2\u10dd\u10e0\u10d8\u10e1 \u10d2\u10d0\u10db\u10dd\u10e7\u10d4\u10dc\u10d4\u10d1\u10d8\u10d7) \u10d3\u10d0 \u10d9\u10d0\u10da\u10ea\u10d8\u10e3\u10db\u10d8\u10e1 \u10d3\u10d0\u10dc\u10d0\u10db\u10d0\u10e2\u10d8, \u10e1\u10d0\u10dc\u10d0\u10db \u10d1\u10d0\u10d5\u10e8\u10d5\u10d8 \u10e1\u10e2\u10d4\u10e0\u10dd\u10d8\u10d3\u10d4\u10d1\u10d6\u10d4 \u10d8\u10db\u10e7\u10dd\u10e4\u10d4\u10d1\u10d0.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u10ea\u10d8\u10d9\u10da\u10dd\u10e1\u10de\u10dd\u10e0\u10d8\u10dc\u10d8 (Ciclosporin)[13]:<\/strong><\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u10e1\u10d0\u10ec\u10e7\u10d8\u10e1\u10d8 \u10d3\u10dd\u10d6\u10d0 \u10e9\u10d5\u10d4\u10e3\u10da\u10d4\u10d1\u10e0\u10d8\u10d5 3 \u10db\u10d2\/\u10d9\u10d2 \u10d3\u10e6\u10d4\u10e8\u10d8 \u10dd\u10e0\u10ef\u10d4\u10e0 \u10d3\u10d0 \u10d3\u10dd\u10d6\u10d8\u10e1 \u10d9\u10dd\u10e0\u10d4\u10e5\u10e2\u10d8\u10e0\u10d4\u10d1\u10d0 \u10e3\u10dc\u10d3\u10d0 \u10db\u10dd\u10ee\u10d3\u10d4\u10e1 \u10e1\u10d8\u10e1\u10ee\u10da\u10e8\u10d8 \u10db\u10d4\u10d3\u10d8\u10d9\u10d0\u10db\u10d4\u10dc\u10e2\u10d8\u10e1 \u10d9\u10dd\u10dc\u10ea\u10d4\u10dc\u10e2\u10e0\u10d0\u10ea\u10d8\u10d8\u10e1 \u10db\u10d8\u10ee\u10d4\u10d3\u10d5\u10d8\u10d7;<\/li>\n\n\n\n<li>3-5 \u10db\u10d2\/\u10d9\u10d2\/\u10d3\u10e6\u10d4 \u10d4\u10dc\u10e2\u10d4\u10e0\u10d0\u10da\u10e3\u10e0\u10d8 \u10d2\u10d6\u10d8\u10d7 \u10d0\u10dc 1-2 \u10db\u10d2\/\u10d9\u10d2\/\u10d3\u10e6\u10d4 IV. <strong>\u10d4\u10dc\u10e2\u10d4\u10e0\u10d0\u10da\u10e3\u10e0\u10d8 \u10d2\u10d6\u10d0 \u10e3\u10de\u10d8\u10e0\u10d0\u10e2\u10d4\u10e1\u10d8\u10d0.<\/strong><\/li>\n\n\n\n<li>\u10db\u10d8\u10d6\u10dc\u10dd\u10d1\u10e0\u10d8\u10d5\u10d8 \u10d9\u10dd\u10dc\u10ea\u10d4\u10dc\u10e2\u10e0\u10d0\u10ea\u10d8\u10d8\u10e1 \u10d3\u10dd\u10dc\u10d4: <strong>100-150 \u03bcg\/l<\/strong>.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\"><strong>\u10d0\u10dc\u10d0\u10d9\u10d8\u10dc\u10e0\u10d0 (Anakinra):<\/strong><\/h3>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u10e1\u10e3\u10d1\u10d9\u10e3\u10e2\u10d0\u10dc\u10e3\u10e0\u10d8 \u10d0\u10dc\u10d0\u10d9\u10d8\u10dc\u10e0\u10d0[14][15][16)]<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>MAS-\u10d8\u10e1 \u10d3\u10e0\u10dd\u10e1 SoJIA-\u10d8\u10e1 \u10d9\u10dd\u10dc\u10e2\u10d4\u10e5\u10e1\u10e2\u10e8\u10d8 <strong>\u10de\u10d8\u10e0\u10d5\u10d4\u10da\u10d0\u10d3\u10d8 \u10d0\u10e0\u10e9\u10d4\u10d5\u10d8\u10e1 \u10d1\u10d8\u10dd\u10da\u10dd\u10d2\u10d8\u10e3\u10e0\u10d8 \u10de\u10e0\u10d4\u10de\u10d0\u10e0\u10d0\u10e2\u10d8\u10d0<\/strong>;<\/li>\n\n\n\n<li>\u10d0\u10e5\u10d5\u10e1 \u10db\u10dd\u10d9\u10da\u10d4 \u10dc\u10d0\u10ee\u10d4\u10d5\u10d0\u10e0\u10d2\u10d0\u10db\u10dd\u10e7\u10dd\u10e4\u10d8\u10e1 \u10de\u10d4\u10e0\u10d8\u10dd\u10d3\u10d8 (\u10d3\u10d0\u10d0\u10ee\u10da\u10dd\u10d4\u10d1\u10d8\u10d7 4-6 \u10e1\u10d0\u10d0\u10d7\u10d8) \u10d3\u10d0 \u10e4\u10d0\u10e0\u10d7\u10dd \u10d7\u10d4\u10e0\u10d0\u10de\u10d8\u10e3\u10da\u10d8 \u10d3\u10d8\u10d0\u10de\u10d0\u10d6\u10dd\u10dc\u10d8;<\/li>\n\n\n\n<li>\u10e9\u10d5\u10d4\u10e3\u10da\u10d4\u10d1\u10e0\u10d8\u10d5 \u10d2\u10d0\u10db\u10dd\u10d8\u10e7\u10d4\u10dc\u10d4\u10d1\u10d0 <strong>2 \u10db\u10d2\/\u10d9\u10d2\/\u10d3\u10e6\u10d4 \u10d3\u10dd\u10d6\u10d8\u10d7<\/strong> S\/C \u10d2\u10d6\u10d8\u10d7 (\u10db\u10d0\u10e5\u10e1\u10d8\u10db\u10d0\u10da\u10e3\u10e0\u10d8 \u10e1\u10d0\u10ec\u10e7\u10d8\u10e1\u10d8 \u10d3\u10dd\u10d6\u10d0: 100 \u10db\u10d2);<\/li>\n\n\n\n<li>\u10d3\u10dd\u10d6\u10d0 \u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0 \u10d2\u10d0\u10d8\u10d6\u10d0\u10e0\u10d3\u10dd\u10e1 \u10db\u10d0\u10e5\u10e1\u10d8\u10db\u10e3\u10db <strong>5 \u10db\u10d2\/\u10d9\u10d2\/\u10d3\u10e6\u10d4\u10e8\u10d8 \u10d0\u10dc \u10e3\u10e4\u10e0\u10dd \u10db\u10d0\u10e6\u10d0\u10da\u10d6\u10d4<\/strong> MAS-\u10d8\u10e1 \u10db\u10d9\u10e3\u10e0\u10dc\u10d0\u10da\u10dd\u10d1\u10d0\u10e8\u10d8 \u10d2\u10d0\u10db\u10dd\u10ea\u10d3\u10d8\u10da\u10d8 \u10e1\u10de\u10d4\u10ea\u10d8\u10d0\u10da\u10d8\u10e1\u10e2\u10d8\u10e1 \u10db\u10d8\u10d7\u10d8\u10d7\u10d4\u10d1\u10d8\u10d7;<\/li>\n\n\n\n<li>\u10d3\u10dd\u10d6\u10d0 \u10e3\u10dc\u10d3\u10d0 \u10d3\u10d0\u10db\u10e0\u10d2\u10d5\u10d0\u10da\u10d3\u10d4\u10e1 \u10e3\u10d0\u10ee\u10da\u10dd\u10d4\u10e1 10 \u10db\u10d2-\u10db\u10d3\u10d4;<\/li>\n\n\n\n<li>\u10e1\u10d8\u10e4\u10e0\u10d7\u10ee\u10d8\u10da\u10d8\u10d7 \u10d2\u10d0\u10db\u10dd\u10d8\u10e7\u10d4\u10dc\u10d4\u10d1\u10d0 \u10e1\u10d0\u10e8\u10e3\u10d0\u10da\u10dd \u10d0\u10dc \u10db\u10eb\u10d8\u10db\u10d4 \u10d7\u10d8\u10e0\u10d9\u10db\u10da\u10d8\u10e1 \u10e4\u10e3\u10dc\u10e5\u10ea\u10d8\u10d8\u10e1 \u10d3\u10d0\u10e0\u10e6\u10d5\u10d4\u10d5\u10d8\u10e1 \u10d3\u10e0\u10dd\u10e1.<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>\u10d8\u10dc\u10e2\u10e0\u10d0\u10d5\u10d4\u10dc\u10e3\u10e0\u10d8 \u10d0\u10dc\u10d0\u10d9\u10d8\u10dc\u10e0\u10d0[17]:<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u10d4\u10e1 \u10d2\u10d6\u10d0 \u10d2\u10d0\u10db\u10dd\u10d8\u10e7\u10d4\u10dc\u10d4\u10d1\u10d0 \u10db\u10d0\u10e8\u10d8\u10dc, \u10e0\u10dd\u10ea\u10d0 \u10d1\u10d0\u10d5\u10e8\u10d5\u10d8 \u10d9\u10e0\u10d8\u10e2\u10d8\u10d9\u10e3\u10da\u10d0\u10d3 \u10db\u10eb\u10d8\u10db\u10d4 \u10db\u10d3\u10d2\u10dd\u10db\u10d0\u10e0\u10d4\u10dd\u10d1\u10d0\u10e8\u10d8\u10d0 \u10d3\u10d0 \u10d0\u10e0\u10e1\u10d4\u10d1\u10dd\u10d1\u10e1 \u10e1\u10d8\u10e1\u10e2\u10d4\u10db\u10e3\u10e0\u10d8 \u10d0\u10d1\u10e1\u10dd\u10e0\u10d1\u10ea\u10d8\u10d8\u10e1 \u10de\u10e0\u10dd\u10d1\u10da\u10d4\u10db\u10d8\u10e1 \u10d4\u10ed\u10d5\u10d8. \u10d4\u10e1 \u10db\u10d4\u10d7\u10dd\u10d3\u10d8 \u10eb\u10d8\u10e0\u10d8\u10d7\u10d0\u10d3\u10d0\u10d3 \u10d8\u10dc\u10e2\u10d4\u10dc\u10e1\u10d8\u10e3\u10e0\u10d8 \u10d7\u10d4\u10e0\u10d0\u10de\u10d8\u10d8\u10e1 \u10d2\u10d0\u10dc\u10e7\u10dd\u10e4\u10d8\u10da\u10d4\u10d1\u10d0\u10e8\u10d8 \u10d2\u10d0\u10db\u10dd\u10d8\u10e7\u10d4\u10dc\u10d4\u10d1\u10d0;<\/li>\n\n\n\n<li>\u10d1\u10d0\u10d5\u10e8\u10d5\u10d4\u10d1\u10e8\u10d8 \u10d3\u10dd\u10d6\u10d8\u10e1 \u10d3\u10d8\u10d0\u10de\u10d0\u10d6\u10dd\u10dc\u10d8 \u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10d2\u10d0\u10db\u10dd\u10e5\u10d5\u10d4\u10e7\u10dc\u10d4\u10d1\u10e3\u10da\u10d8;<\/li>\n\n\n\n<li>\u10e1\u10d0\u10ec\u10e7\u10d8\u10e1\u10d8 \u10d3\u10dd\u10d6\u10d0: <strong>2 \u10db\u10d2\/\u10d9\u10d2 (\u10db\u10d0\u10e5\u10e1\u10d8\u10db\u10e3\u10db 100 \u10db\u10d2)<\/strong>, \u10e0\u10d0\u10e1\u10d0\u10ea \u10db\u10dd\u10e1\u10d3\u10d4\u10d5\u10e1 \u10e3\u10ec\u10e7\u10d5\u10d4\u10e2\u10d8 \u10d8\u10dc\u10e4\u10e3\u10d6\u10d8\u10d0, \u10d3\u10d0\u10ec\u10e7\u10d4\u10d1\u10e3\u10da\u10d8 2 \u10db\u10d2\/\u10d9\u10d2\/\u10d3\u10e6\u10d4, \u10e0\u10dd\u10db\u10da\u10d8\u10e1 \u10d2\u10d0\u10d6\u10e0\u10d3\u10d0\u10ea \u10e8\u10d4\u10e1\u10d0\u10eb\u10da\u10d4\u10d1\u10d4\u10da\u10d8\u10d0 \u10e1\u10de\u10d4\u10ea\u10d8\u10d0\u10da\u10d8\u10e1\u10e2\u10d8\u10e1 \u10db\u10d8\u10d7\u10d8\u10d7\u10d4\u10d1\u10d8\u10d7;<\/li>\n\n\n\n<li>\u10d0\u10dc\u10d0\u10d9\u10d8\u10dc\u10e0\u10d0 \u10e3\u10e1\u10d0\u10e4\u10e0\u10d7\u10ee\u10dd\u10d0 \u10d3\u10d0 <strong>\u10e1\u10d4\u10e4\u10e1\u10d8\u10e1\u10d8\u10e1 \u10d3\u10e0\u10dd\u10e1 \u10da\u10d4\u10e2\u10d0\u10da\u10dd\u10d1\u10d0\u10e1 \u10d0\u10e0 \u10d6\u10e0\u10d3\u10d8\u10e1[18)]<\/strong><\/li>\n<\/ul>\n\n\n\n<p><strong>IV \u10d8\u10db\u10e3\u10dc\u10dd\u10d2\u10da\u10dd\u10d1\u10e3\u10da\u10d8\u10dc\u10d8:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u10d9\u10dd\u10dc\u10d9\u10e0\u10d4\u10e2\u10e3\u10da \u10e8\u10d4\u10db\u10d7\u10ee\u10d5\u10d4\u10d5\u10d4\u10d1\u10e8\u10d8 IVIG \u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0 \u10d2\u10d0\u10db\u10dd\u10e7\u10d4\u10dc\u10d4\u10d1\u10e3\u10da \u10d8\u10e5\u10dc\u10d0\u10e1 \u10d9\u10dd\u10db\u10d1\u10d8\u10dc\u10d8\u10e0\u10d4\u10d1\u10e3\u10da\u10d8 \u10d7\u10d4\u10e0\u10d0\u10de\u10d8\u10d8\u10e1 \u10e4\u10d0\u10e0\u10d2\u10da\u10d4\u10d1\u10e8\u10d8 \u10d1\u10d0\u10d5\u10e8\u10d5\u10d7\u10d0 \u10e0\u10d4\u10d5\u10db\u10d0\u10e2\u10dd\u10da\u10dd\u10d2\u10d8\u10e1 \u10db\u10d8\u10d7\u10d8\u10d7\u10d4\u10d1\u10d8\u10d7.<\/li>\n<\/ul>\n\n\n\n<p><strong>\u10d0\u10dc\u10e2\u10d8\u10d1\u10d8\u10dd\u10e2\u10d8\u10d9\u10d4\u10d1\u10d8:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u10e4\u10d0\u10e0\u10d7\u10dd \u10e1\u10de\u10d4\u10e5\u10e2\u10e0\u10d8\u10e1 \u10d0\u10dc\u10e2\u10d8\u10d1\u10d8\u10dd\u10e2\u10d8\u10d9\u10d4\u10d1\u10d8 \u10e3\u10dc\u10d3\u10d0 \u10d3\u10d0\u10d8\u10dc\u10d8\u10e8\u10dc\u10dd\u10e1 \u10db\u10d0\u10dc\u10d0\u10db, \u10e1\u10d0\u10dc\u10d0\u10db \u10d1\u10d0\u10e5\u10e2\u10d4\u10e0\u10d8\u10e3\u10da\u10d8 \u10d8\u10dc\u10e4\u10d4\u10e5\u10ea\u10d8\u10d0 \u10d2\u10d0\u10db\u10dd\u10d8\u10e0\u10d8\u10ea\u10ee\u10d4\u10d1\u10d0.<\/li>\n<\/ul>\n\n\n\n<p><strong>\u10d3\u10d0\u10db\u10d0\u10e2\u10d4\u10d1\u10d8\u10d7\u10d8 \u10db\u10dd\u10e1\u10d0\u10d6\u10e0\u10d4\u10d1\u10d4\u10d1\u10d8<\/strong><\/p>\n\n\n\n<p><strong>\u10de\u10d8\u10e0\u10d5\u10d4\u10da\u10d0\u10d3\u10d8 HLH:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u10e8\u10d4\u10e3\u10eb\u10da\u10d8\u10d0 \u10db\u10e1\u10d2\u10d0\u10d5\u10e1\u10d8 \u10d9\u10da\u10d8\u10dc\u10d8\u10d9\u10e3\u10e0\u10d8 \u10e1\u10e3\u10e0\u10d0\u10d7\u10d8\u10e1 \u10d2\u10d0\u10db\u10dd\u10d5\u10da\u10d4\u10dc\u10d0, \u10e0\u10dd\u10d2\u10dd\u10e0\u10ea \u10db\u10d4\u10dd\u10e0\u10d0\u10d3 HLH-\u10e1;<\/li>\n\n\n\n<li>\u10e9\u10d5\u10d4\u10e3\u10da\u10d4\u10d1\u10e0\u10d8\u10d5 \u10d5\u10da\u10d8\u10dc\u10d3\u10d4\u10d1\u10d0 \u10d1\u10d0\u10d5\u10e8\u10d5\u10d4\u10d1\u10e8\u10d8, \u10e3\u10db\u10d4\u10e2\u10d4\u10e1\u10d0\u10d3 \u10e1\u10d8\u10ea\u10dd\u10ea\u10ee\u10da\u10d8\u10e1 \u10de\u10d8\u10e0\u10d5\u10d4\u10da \u10dd\u10e0 \u10ec\u10d4\u10da\u10e1;<\/li>\n\n\n\n<li>\u10d4\u10ed\u10d5\u10d8\u10e1 \u10e8\u10d4\u10db\u10d7\u10ee\u10d5\u10d4\u10d5\u10d0\u10e8\u10d8 \u10e3\u10dc\u10d3\u10d0 \u10e9\u10d0\u10e2\u10d0\u10e0\u10d3\u10d4\u10e1 \u10d9\u10dd\u10dc\u10e1\u10e3\u10da\u10e2\u10d0\u10ea\u10d8\u10d0 \u10d8\u10dc\u10e4\u10d4\u10e5\u10ea\u10d8\u10dd\u10dc\u10d8\u10e1\u10e2\u10d7\u10d0\u10dc \u10d0\u10dc \u10d8\u10db\u10e3\u10dc\u10dd\u10da\u10dd\u10d2\u10d7\u10d0\u10dc;<\/li>\n\n\n\n<li>\u10e1\u10d9\u10e0\u10d8\u10dc\u10d8\u10dc\u10d2\u10d8 \u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0 \u10db\u10dd\u10d8\u10ea\u10d0\u10d5\u10d3\u10d4\u10e1:\n<ul class=\"wp-block-list\">\n<li>\u10de\u10d4\u10e0\u10e4\u10dd\u10e0\u10d8\u10dc\u10e1;<\/li>\n\n\n\n<li>\u10d2\u10e0\u10d0\u10dc\u10e3\u10da\u10d4\u10d1\u10d8\u10e1 \u10d2\u10d0\u10db\u10dd\u10e7\u10dd\u10e4\u10d8\u10e1 \u10e2\u10d4\u10e1\u10e2\u10e1 (GRA);<\/li>\n\n\n\n<li>\u10d3\u10d0 \u10d1\u10d8\u10ed\u10d4\u10d1\u10e8\u10d8 SAP (Signal Lymphocyte Activating Molecule Associated Protein) \u10d3\u10d0 XIAP (X-linked Inhibitor of Apoptosis Protein) \u10d4\u10e5\u10e1\u10de\u10e0\u10d4\u10e1\u10d8\u10d0\u10d6\u10d4 \u10e1\u10d9\u10e0\u10d8\u10dc\u10d8\u10dc\u10d2\u10e1.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<p><strong>\u10d8\u10dc\u10e4\u10d4\u10e5\u10ea\u10d8\u10e3\u10e0\u10d8 \u10e2\u10e0\u10d8\u10d2\u10d4\u10e0\u10d8:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u10e1\u10e3\u10da \u10e3\u10e4\u10e0\u10dd \u10db\u10d4\u10e2\u10d0\u10d3 \u10db\u10e7\u10d0\u10e0\u10d3\u10d4\u10d1\u10d0 \u10d0\u10d6\u10e0\u10d8, \u10e0\u10dd\u10db MAS-\u10d8\u10e1 \u10d4\u10de\u10d8\u10d6\u10dd\u10d3\u10d8 \u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0 \u10d2\u10d0\u10db\u10dd\u10ec\u10d5\u10d4\u10e3\u10da\u10d8 \u10d8\u10e7\u10dd\u10e1 \u10d7\u10d0\u10dc\u10db\u10ee\u10da\u10d4\u10d1\u10d8 \u10d8\u10dc\u10e4\u10d4\u10e5\u10ea\u10d8\u10d8\u10d7 \u10d8\u10db \u10d1\u10d0\u10d5\u10e8\u10d5\u10d4\u10d1\u10e8\u10d8, \u10e0\u10dd\u10db\u10da\u10d4\u10d1\u10e1\u10d0\u10ea \u10d0\u10e5\u10d5\u10d7 \u10e0\u10d4\u10d5\u10db\u10d0\u10e2\u10dd\u10da\u10dd\u10d2\u10d8\u10e3\u10e0\u10d8 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10d6\u10d8 \u10d3\u10d0 \u10d2\u10d4\u10dc\u10d4\u10e2\u10d8\u10d9\u10e3\u10e0\u10d8 \u10db\u10d8\u10d3\u10e0\u10d4\u10d9\u10d8\u10da\u10d4\u10d1\u10d0;<\/li>\n\n\n\n<li>\u10e1\u10d0\u10ed\u10d8\u10e0\u10dd\u10d0 \u10e1\u10e0\u10e3\u10da\u10e7\u10dd\u10e4\u10d8\u10da\u10d8 \u10d8\u10dc\u10e4\u10d4\u10e5\u10ea\u10d8\u10e3\u10e0\u10d8 \u10e1\u10d9\u10e0\u10d8\u10dc\u10d8\u10dc\u10d2\u10d8, \u10db\u10d0\u10d7 \u10e8\u10dd\u10e0\u10d8\u10e1:\n<ul class=\"wp-block-list\">\n<li>\u10d5\u10d8\u10e0\u10e3\u10e1\u10e3\u10da\u10d8 \u10d3\u10d0 \u10d1\u10d0\u10e5\u10e2\u10d4\u10e0\u10d8\u10e3\u10da\u10d8 \u10d8\u10dc\u10e4\u10d4\u10e5\u10ea\u10d8\u10d4\u10d1\u10d8\u10e1 \u10d2\u10d0\u10db\u10dd\u10d9\u10d5\u10da\u10d4\u10d5\u10d0 \u10de\u10d8\u10e0-\u10ee\u10d0\u10ee\u10d8\u10e1 \u10dc\u10d0\u10ea\u10ee\u10e8\u10d8;<\/li>\n\n\n\n<li>\u10e1\u10d8\u10e1\u10ee\u10da\u10d8\u10e1 \u10d1\u10d0\u10e5\u10e2\u10d4\u10e0\u10d8\u10dd\u10da\u10dd\u10d2\u10d8\u10e3\u10e0\u10d8 \u10d2\u10d0\u10db\u10dd\u10d9\u10d5\u10da\u10d4\u10d5\u10d0;<\/li>\n\n\n\n<li>\u10e8\u10d0\u10e0\u10d3\u10d8\u10e1 \u10d1\u10d0\u10e5\u10e2\u10d4\u10e0\u10d8\u10dd\u10da\u10dd\u10d2\u10d8\u10e3\u10e0\u10d8 \u10d2\u10d0\u10db\u10dd\u10d9\u10d5\u10da\u10d4\u10d5\u10d0;<\/li>\n\n\n\n<li>\u10d5\u10d8\u10e0\u10e3\u10e1\u10e3\u10da\u10d8 \u10d3\u10d0 \u10d1\u10d0\u10e5\u10e2\u10d4\u10e0\u10d8\u10e3\u10da\u10d8 \u10e2\u10d4\u10e1\u10e2\u10d4\u10d1\u10d8 \u10d2\u10d0\u10dc\u10d0\u10d5\u10d0\u10da\u10e8\u10d8 (\u10e9\u10d5\u10d4\u10dc\u10d4\u10d1\u10d8\u10e1 \u10db\u10d8\u10ee\u10d4\u10d3\u10d5\u10d8\u10d7),<\/li>\n\n\n\n<li>O-\u10d0\u10dc\u10e2\u10d8\u10e1\u10e2\u10e0\u10d4\u10de\u10e2\u10dd\u10da\u10d8\u10d6\u10d8\u10dc\u10d8\u10e1 \u10e2\u10d8\u10e2\u10e0\u10d8;<\/li>\n\n\n\n<li>\u10d5\u10d8\u10e0\u10e3\u10e1\u10d4\u10d1\u10d8\u10e1 \u10e1\u10d4\u10e0\u10dd\u10da\u10dd\u10d2\u10d8\u10d0\/PCR \u10d8\u10e1\u10d4\u10d7\u10d8 \u10dd\u10e0\u10d2\u10d0\u10dc\u10d8\u10d6\u10db\u10d4\u10d1\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1, \u10e0\u10dd\u10d2\u10dd\u10e0\u10d8\u10ea\u10d0\u10d0 \u10d0\u10d3\u10d4\u10dc\u10dd\u10d5\u10d8\u10e0\u10e3\u10e1\u10d8, EBV, CMV, HSV, VZV, HHV 6 \u10d3\u10d0 7.<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li>\u10d5\u10d8\u10e0\u10e3\u10e1\u10e3\u10da\u10d8 PCR\/\u10e1\u10d4\u10e0\u10dd\u10da\u10dd\u10d2\u10d8\u10e3\u10e0\u10d8 \u10e2\u10d4\u10e1\u10e2\u10d4\u10d1\u10d8\u10e1 \u10ee\u10d4\u10da\u10db\u10d8\u10e1\u10d0\u10ec\u10d5\u10d3\u10dd\u10db\u10dd\u10d1\u10d0 \u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0 \u10d2\u10d0\u10dc\u10e1\u10ee\u10d5\u10d0\u10d5\u10d3\u10d4\u10d1\u10dd\u10d3\u10d4\u10e1 \u10e1\u10d0\u10d0\u10d5\u10d0\u10d3\u10db\u10e7\u10dd\u10e4\u10dd\u10d4\u10d1\u10e1 \u10e8\u10dd\u10e0\u10d8\u10e1 \u10d3\u10d0 \u10e1\u10d0\u10ed\u10d8\u10e0\u10dd\u10d0 \u10d2\u10d0\u10dc\u10ee\u10d8\u10da\u10d5\u10d0 \u10d0\u10d3\u10d2\u10d8\u10da\u10dd\u10d1\u10e0\u10d8\u10d5 \u10d0\u10dc \u10e0\u10d4\u10d2\u10d8\u10dd\u10dc\u10e3\u10da \u10d3\u10dd\u10dc\u10d4\u10d6\u10d4.<\/li>\n<\/ul>\n\n\n\n<p><strong>\u10db\u10d4\u10d3\u10d8\u10d9\u10d0\u10db\u10d4\u10dc\u10e2\u10d4\u10d1\u10d8:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u10e0\u10d4\u10d5\u10db\u10d0\u10e2\u10dd\u10da\u10dd\u10d2\u10d8\u10e3\u10e0\u10d8 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10d6\u10d8\u10e1 \u10db\u10e5\u10dd\u10dc\u10d4 \u10d1\u10d0\u10d5\u10e8\u10d5\u10d4\u10d1\u10e8\u10d8 \u10db\u10d9\u10e3\u10e0\u10dc\u10d0\u10da\u10dd\u10d1\u10d8\u10e1 \u10e8\u10d4\u10ea\u10d5\u10da\u10d0\u10db \u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0 \u10d2\u10d0\u10db\u10dd\u10d8\u10ec\u10d5\u10d8\u10dd\u10e1 MAS-\u10d8\u10e1 \u10d4\u10de\u10d8\u10d6\u10dd\u10d3\u10d8, \u10ee\u10dd\u10da\u10dd \u10d1\u10d8\u10dd\u10da\u10dd\u10d2\u10d8\u10e3\u10e0\u10db\u10d0 \u10de\u10e0\u10d4\u10de\u10d0\u10e0\u10d0\u10e2\u10d4\u10d1\u10db\u10d0 \u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0 \u10d2\u10d0\u10d5\u10da\u10d4\u10dc\u10d0 \u10db\u10dd\u10d0\u10ee\u10d3\u10d8\u10dc\u10dd\u10e1 \u10d9\u10da\u10d8\u10dc\u10d8\u10d9\u10e3\u10e0 \u10e1\u10e3\u10e0\u10d0\u10d7\u10d6\u10d4 (\u10db\u10d0\u10d2\u10d0\u10da\u10d8\u10d7\u10d0\u10d3, \u10e2\u10dd\u10ea\u10d8\u10da\u10d8\u10d6\u10e3\u10db\u10d0\u10d1\u10db\u10d0 \u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0 \u10ee\u10d4\u10da\u10d8 \u10e8\u10d4\u10e3\u10e8\u10d0\u10da\u10dd\u10e1 \u10ea\u10ee\u10d4\u10da\u10d4\u10d1\u10d8\u10e1 \u10d0\u10e6\u10db\u10dd\u10ea\u10d4\u10dc\u10d4\u10d1\u10d0\u10e1 \u10d3\u10d0 CRP-\u10d8\u10e1 \u10db\u10d0\u10e2\u10d4\u10d1\u10d0\u10e1).<\/li>\n<\/ul>\n\n\n\n<p class=\"has-vivid-red-color has-text-color has-link-color wp-elements-c0bf5758133bb299d78e56e3d9586246\" style=\"font-style:normal;font-weight:700\">\u10e1\u10e2\u10d0\u10e2\u10d8\u10d0 \u10db\u10dd\u10db\u10d6\u10d0\u10d3\u10d4\u10d1\u10e3\u10da\u10d8\u10d0 \u10e8\u10dd\u10e2\u10da\u10d0\u10dc\u10d3\u10d8\u10d8\u10e1 \u10d1\u10d0\u10d5\u10e8\u10d5\u10d7\u10d0 \u10d3\u10d0 \u10db\u10dd\u10d6\u10d0\u10e0\u10d3\u10d7\u10d0 \u10e0\u10d4\u10d5\u10db\u10d0\u10e2\u10dd\u10da\u10dd\u10d2\u10d8\u10d8\u10e1 \u10e5\u10e1\u10d4\u10da\u10d8\u10e1 \u10d2\u10d0\u10d8\u10d3\u10da\u10d0\u10d8\u10dc\u10d8\u10e1 &#8220;\u10db\u10d0\u10d9\u10e0\u10dd\u10e4\u10d0\u10d2\u10d4\u10d1\u10d8\u10e1 \u10d0\u10e5\u10e2\u10d8\u10d5\u10d0\u10ea\u10d8\u10d8\u10e1 \u10e1\u10d8\u10dc\u10d3\u10e0\u10dd\u10db\u10d8\u10e1 \u10e1\u10d0\u10ec\u10e7\u10d8\u10e1\u10d8 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10d6\u10d8&#8221; \u10db\u10d8\u10ee\u10d4\u10d3\u10d5\u10d8\u10d7.<\/p>\n\n\n\n<p class=\"has-vivid-purple-color has-text-color has-link-color wp-elements-46ccb3fef47ae338a724932f189764cc\" style=\"font-style:italic;font-weight:400\">\u10d2\u10d0\u10e4\u10e0\u10d7\u10ee\u10d8\u10da\u10d4\u10d1\u10d0: \u10d4\u10e1 \u10d2\u10d0\u10d8\u10d3\u10da\u10d0\u10d8\u10dc\u10d8 \u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10d2\u10d0\u10dc\u10d9\u10e3\u10d7\u10d5\u10dc\u10d8\u10da\u10d8 \u10d8\u10db\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1, \u10e0\u10dd\u10db \u10d0\u10e6\u10d8\u10e5\u10db\u10d4\u10d1\u10dd\u10d3\u10d4\u10e1 \u10d0\u10dc \u10d2\u10d0\u10db\u10dd\u10d8\u10e7\u10d4\u10dc\u10d4\u10d1\u10dd\u10d3\u10d4\u10e1, \u10e0\u10dd\u10d2\u10dd\u10e0\u10ea \u10e1\u10d0\u10db\u10e3\u10e8\u10d0\u10dd \u10e1\u10e2\u10d0\u10dc\u10d3\u10d0\u10e0\u10e2\u10d8. \u10e1\u10d0\u10db\u10e3\u10e8\u10d0\u10dd \u10e1\u10e2\u10d0\u10dc\u10d3\u10d0\u10e0\u10e2\u10d4\u10d1\u10d8 \u10d2\u10d0\u10dc\u10d8\u10e1\u10d0\u10d6\u10e6\u10d5\u10e0\u10d4\u10d1\u10d0 \u10d9\u10dd\u10dc\u10d9\u10e0\u10d4\u10e2\u10e3\u10da\u10d8 \u10e8\u10d4\u10db\u10d7\u10ee\u10d5\u10d4\u10d5\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1 \u10ee\u10d4\u10da\u10db\u10d8\u10e1\u10d0\u10ec\u10d5\u10d3\u10dd\u10db\u10d8 \u10e7\u10d5\u10d4\u10da\u10d0 \u10d9\u10da\u10d8\u10dc\u10d8\u10d9\u10e3\u10e0\u10d8 \u10db\u10dd\u10dc\u10d0\u10ea\u10d4\u10db\u10d8\u10e1 \u10e1\u10d0\u10e4\u10e3\u10eb\u10d5\u10d4\u10da\u10d6\u10d4 \u10d3\u10d0 \u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0 \u10e8\u10d4\u10d8\u10ea\u10d5\u10d0\u10da\u10dd\u10e1, \u10e1\u10d0\u10db\u10d4\u10ea\u10dc\u10d8\u10d4\u10e0\u10dd \u10ea\u10dd\u10d3\u10dc\u10d8\u10e1 \u10d3\u10d0 \u10e2\u10d4\u10e5\u10dc\u10dd\u10da\u10dd\u10d2\u10d8\u10d4\u10d1\u10d8\u10e1 \u10d2\u10d0\u10dc\u10d5\u10d8\u10d7\u10d0\u10e0\u10d4\u10d1\u10d0\u10e1\u10d7\u10d0\u10dc \u10d4\u10e0\u10d7\u10d0\u10d3. \u10d2\u10d0\u10d8\u10d3\u10da\u10d0\u10d8\u10dc\u10d8\u10e1 \u10e0\u10d4\u10d9\u10dd\u10db\u10d4\u10dc\u10d3\u10d0\u10ea\u10d8\u10d4\u10d1\u10d8\u10e1 \u10d3\u10d0\u10ea\u10d5\u10d0 \u10d0\u10e0 \u10e3\u10d6\u10e0\u10e3\u10dc\u10d5\u10d4\u10da\u10e7\u10dd\u10e4\u10e1 \u10ec\u10d0\u10e0\u10db\u10d0\u10e2\u10d4\u10d1\u10e3\u10da \u10e8\u10d4\u10d3\u10d4\u10d2\u10e1 \u10e7\u10d5\u10d4\u10da\u10d0 \u10e8\u10d4\u10db\u10d7\u10ee\u10d5\u10d4\u10d5\u10d0\u10e8\u10d8. \u10e1\u10d0\u10d1\u10dd\u10da\u10dd\u10dd \u10d2\u10d0\u10d3\u10d0\u10ec\u10e7\u10d5\u10d4\u10e2\u10d8\u10da\u10d4\u10d1\u10d0 \u10e3\u10dc\u10d3\u10d0 \u10db\u10d8\u10d8\u10e6\u10dd\u10e1 \u10e8\u10d4\u10e1\u10d0\u10d1\u10d0\u10db\u10d8\u10e1\u10db\u10d0 \u10ef\u10d0\u10dc\u10d3\u10d0\u10ea\u10d5\u10d8\u10e1 \u10de\u10e0\u10dd\u10e4\u10d4\u10e1\u10d8\u10dd\u10dc\u10d0\u10da\u10db\u10d0(\u10d4\u10d1\u10db\u10d0), \u10e0\u10dd\u10db\u10da\u10d4\u10d1\u10d8\u10ea \u10de\u10d0\u10e1\u10e3\u10ee\u10d8\u10e1\u10db\u10d2\u10d4\u10d1\u10d4\u10da\u10dc\u10d8 \u10d0\u10e0\u10d8\u10d0\u10dc \u10d9\u10da\u10d8\u10dc\u10d8\u10d9\u10e3\u10e0 \u10d2\u10d0\u10d3\u10d0\u10ec\u10e7\u10d5\u10d4\u10e2\u10d8\u10da\u10d4\u10d1\u10d4\u10d1\u10d6\u10d4 \u10d9\u10dd\u10dc\u10d9\u10e0\u10d4\u10e2\u10e3\u10da\u10d8 \u10de\u10e0\u10dd\u10ea\u10d4\u10d3\u10e3\u10e0\u10d8\u10e1 \u10d0\u10dc \u10db\u10d9\u10e3\u10e0\u10dc\u10d0\u10da\u10dd\u10d1\u10d8\u10e1 \u10d2\u10d4\u10d2\u10db\u10d8\u10e1 \u10e8\u10d4\u10e1\u10d0\u10ee\u10d4\u10d1. \u10d4\u10e1 \u10d2\u10d0\u10d3\u10d0\u10ec\u10e7\u10d5\u10d4\u10e2\u10d8\u10da\u10d4\u10d1\u10d0 \u10db\u10d8\u10e6\u10d4\u10d1\u10e3\u10da \u10e3\u10dc\u10d3\u10d0 \u10d8\u10e5\u10dc\u10d0\u10e1 \u10db\u10ee\u10dd\u10da\u10dd\u10d3 \u10db\u10d0\u10e1 \u10e8\u10d4\u10db\u10d3\u10d4\u10d2, \u10e0\u10d0\u10ea \u10de\u10d0\u10ea\u10d8\u10d4\u10dc\u10e2\u10d8\u10e1 \u10e8\u10d4\u10db\u10d7\u10ee\u10d5\u10d4\u10d5\u10d0\u10e8\u10d8 \u10d2\u10d0\u10dc\u10d8\u10ee\u10d8\u10da\u10d4\u10d1\u10d0 \u10d0\u10e0\u10e1\u10d4\u10d1\u10e3\u10da\u10d8 \u10d3\u10d8\u10d0\u10d2\u10dc\u10dd\u10e1\u10e2\u10d8\u10d9\u10e3\u10e0\u10d8 \u10d3\u10d0 \u10db\u10d9\u10e3\u10e0\u10dc\u10d0\u10da\u10dd\u10d1\u10d8\u10e1 \u10d5\u10d0\u10e0\u10d8\u10d0\u10dc\u10e2\u10d4\u10d1\u10d8. \u10e0\u10d4\u10d9\u10dd\u10db\u10d4\u10dc\u10d3\u10d4\u10d1\u10e3\u10da\u10d8\u10d0, \u10e0\u10dd\u10db \u10d4\u10e0\u10dd\u10d5\u10dc\u10e3\u10da\u10d8 \u10d2\u10d0\u10d8\u10d3\u10da\u10d0\u10d8\u10dc\u10d8\u10e1 \u10d0\u10dc \u10db\u10d8\u10e1\u10d2\u10d0\u10dc \u10ec\u10d0\u10e0\u10db\u10dd\u10d4\u10d1\u10e3\u10da\u10d8 \u10d0\u10d3\u10d2\u10d8\u10da\u10dd\u10d1\u10e0\u10d8\u10d5\u10d8 \u10e1\u10d0\u10ee\u10d4\u10da\u10db\u10eb\u10e6\u10d5\u10d0\u10dc\u10d4\u10da\u10dd\u10d4\u10d1\u10d8\u10e1 \u10db\u10dc\u10d8\u10e8\u10d5\u10dc\u10d4\u10da\u10dd\u10d5\u10d0\u10dc\u10d8 \u10d2\u10d0\u10d3\u10d0\u10ee\u10d5\u10d4\u10d5\u10d4\u10d1\u10d8 \u10e1\u10e0\u10e3\u10da\u10d0\u10d3 \u10d3\u10d0\u10e4\u10d8\u10e5\u10e1\u10d8\u10e0\u10d3\u10d4\u10e1 \u10de\u10d0\u10ea\u10d8\u10d4\u10dc\u10e2\u10d8\u10e1 \u10e1\u10d0\u10db\u10d4\u10d3\u10d8\u10ea\u10d8\u10dc\u10dd \u10e9\u10d0\u10dc\u10d0\u10ec\u10d4\u10e0\u10d4\u10d1\u10e8\u10d8 \u10d8\u10db \u10db\u10dd\u10db\u10d4\u10dc\u10e2\u10e8\u10d8, \u10e0\u10dd\u10d3\u10d4\u10e1\u10d0\u10ea \u10e8\u10d4\u10e1\u10d0\u10d1\u10d0\u10db\u10d8\u10e1\u10d8 \u10d2\u10d0\u10d3\u10d0\u10ec\u10e7\u10d5\u10d4\u10e2\u10d8\u10da\u10d4\u10d1\u10d0 \u10db\u10d8\u10d8\u10e6\u10d4\u10d1\u10d0.<\/p>\n\n\n\n<p>\u10da\u10d8\u10e2\u10d4\u10e0\u10d0\u10e2\u10e3\u10e0\u10d0:<\/p>\n\n\n\n<ul>\n  <li>Henderson LA. Deciphering the cytokine fingerprint of macrophage activation syndrome. <em>Lancet Rheumatol.<\/em> 2021 Aug 1;3(8):e535\u20138.<\/li>\n  <li>Crayne C, Cron RQ. Pediatric macrophage activation syndrome, recognizing the tip of the Iceberg. <em>Eur J Rheumatol.<\/em> 2019 Dec 3;7(Suppl 1):1\u20138.<\/li>\n  <li>Sawhney S, Woo P, Murray KJ. Macrophage activation syndrome: A potentially fatal complication of rheumatic disorders. <em>Arch Dis Child.<\/em> 2001 Dec 1;85:421\u20136.<\/li>\n  <li>Minoia F, Dav\u00ec S, Horne A, Demirkaya E, Bovis F, Li C, et al. Clinical Features, Treatment, and Outcome of Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis: A Multinational, Multicenter Study of 362 Patients. <em>Arthritis Rheumatol.<\/em> 2014 Nov 1;66(11):3160\u20139.<\/li>\n  <li>McLellan K, MacGregor I, Martin N, Davidson J. Macrophage activation syndrome- a case series. <em>Pediatr Rheumatol Online J.<\/em> 2015;14(Supplement 1):164\u20135.<\/li>\n  <li>Henter J-I, Horne A, Aric\u00f3 M, Egeler RM, Filipovich AH, Imashuku S, et al. HLH2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. <em>Pediatr Blood Cancer.<\/em> 2007 Feb 1;48(2):124\u201331.<\/li>\n  <li>Grom AA, Horne A, De Benedetti F. Macrophage activation syndrome in the era of biologic therapy. <em>Nat Rev Rheumatol.<\/em> 2016 May;12(5):259\u201368.<\/li>\n  <li>Brisse E, Wouters CH, Matthys P. Advances in the pathogenesis of primary and secondary haemophagocytic lymphohistiocytosis: differences and similarities. <em>Br J Haematol.<\/em> 2016 Jul 1;174(2):203\u201317.<\/li>\n  <li>Allen CE, Yu X, Kozinetz CA, McClain KL. Highly elevated ferritin levels and the diagnosis of hemophagocytic lymphohistiocytosis. <em>Pediatr Blood Cancer.<\/em> 2008 Jun 1;50(6):1227\u201335.<\/li>\n  <li>Ravelli A, Minoia F, Dav\u00ec S, Horne A, Bovis F, Pistorio A, et al. 2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis. <em>Ann Rheum Dis.<\/em> 2016 Mar 1;75(3):481.<\/li>\n  <li>Ravelli A, Magni-Manzoni S, Pistorio A, Besana C, Foti T, Ruperto N, et al. Preliminary diagnostic guidelines for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis. <em>J Pediatr.<\/em> 2005 May 1;146(5):598\u2013604.<\/li>\n  <li>Parodi A, Dav\u00ec S, Pringe AB, Pistorio A, Ruperto N, Magni-Manzoni S, et al. Macrophage activation syndrome in juvenile systemic lupus erythematosus: A multinational multicenter study of thirty-eight patients. <em>Arthritis Rheum.<\/em> 2009 Nov 1;60(11):3388\u201399.<\/li>\n  <li>Mouy R, Stephan J-L, Pillet P, Haddad E, Hubert P, Prieur A-M. Efficacy of cyclosporine A in the treatment of macrophage activation syndrome in juvenile arthritis: Report of five cases. <em>J Pediatr.<\/em> 1996 Nov 1;129(5):750\u20134.<\/li>\n  <li>Kumar A, Kato H. Macrophage Activation Syndrome Associated with Adult-Onset Still\u2019s Disease Successfully Treated with Anakinra. <em>Case Rep Rheumatol.<\/em> 2016;2016:3717392\u20133717392.<\/li>\n  <li>Nahata MC, Morosco RS, Sabados BK, Weber TR. Stability and compatibility of anakinra with intravenous cimetidine hydrochloride or famotidine in 0.9% sodium chloride injection. <em>J Clin Pharm Ther.<\/em> 1995 Apr 1;20(2):97\u20139.<\/li>\n  <li>Granowitz EV, Porat R, Mier JW, Pribble JP, Stiles DM, Bloedow DC, et al. Pharmacokinetics, safety and immunomodulatory effects of human recombinant interleukin-1 receptor antagonist in healthy humans. <em>Cytokine.<\/em> 1992 Sep 1;4(5):353\u201360.<\/li>\n  <li>Galea J, Ogungbenro K, Hulme S, Greenhalgh A, Aarons L, Scarth S, et al. Intravenous anakinra can achieve experimentally effective concentrations in the central nervous system within a therapeutic time window: results of a dose-ranging study. <em>J Cereb Blood Flow Metab.<\/em> 2011 Feb;31(2):439\u201347.<\/li>\n  <li>Shakoory B, Carcillo JA, Chatham WW, Amdur RL, Zhao H, Dinarello CA, et al. Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome: Reanalysis of a Prior Phase III Trial. <em>Crit Care Med.<\/em> 2016 Feb;44(2):275\u201381.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u10db\u10d0\u10d9\u10e0\u10dd\u10e4\u10d0\u10d2\u10d4\u10d1\u10d8\u10e1 \u10d0\u10e5\u10e2\u10d8\u10d5\u10d0\u10ea\u10d8\u10d8\u10e1 \u10e1\u10d8\u10dc\u10d3\u10e0\u10dd\u10db\u10d8 (MAS) \u10d0\u10e0\u10d8\u10e1 \u10d8\u10e8\u10d5\u10d8\u10d0\u10d7\u10d8 \u10f0\u10d8\u10de\u10d4\u10e0\u10d0\u10dc\u10d7\u10d4\u10d1\u10d8\u10d7\u10d8 \u10db\u10d3\u10d2\u10dd\u10db\u10d0\u10e0\u10d4\u10dd\u10d1\u10d0, \u10e0\u10dd\u10db\u10d4\u10da\u10d8\u10ea \u10ec\u10d0\u10e0\u10db\u10dd\u10d0\u10d3\u10d2\u10d4\u10dc\u10e1 \u10ea\u10d8\u10e2\u10dd\u10d9\u10d8\u10dc\u10e3\u10e0\u10d8 \u10e8\u10e2\u10dd\u10e0\u10db\u10d8\u10e1 \u10d4\u10e0\u10d7-\u10d4\u10e0\u10d7 \u10dc\u10d0\u10d8\u10e0\u10e1\u10d0\u10ee\u10d4\u10dd\u10d1\u10d0\u10e1 [1][2]. \u10d4\u10e1 \u10db\u10d3\u10d2\u10dd\u10db\u10d0\u10e0\u10d4\u10dd\u10d1\u10d0 \u10e8\u10d4\u10d8\u10eb\u10da\u10d4\u10d1\u10d0<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[63,64,8,9,11,61,62],"class_list":["post-516","post","type-post","status-publish","format-standard","hentry","category-klinikuri-rchevebi","tag-mis-c","tag-64","tag-8","tag-9","tag-11","tag-61","tag-62"],"_links":{"self":[{"href":"https:\/\/icu.ge\/index.php?rest_route=\/wp\/v2\/posts\/516","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/icu.ge\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/icu.ge\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/icu.ge\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/icu.ge\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=516"}],"version-history":[{"count":0,"href":"https:\/\/icu.ge\/index.php?rest_route=\/wp\/v2\/posts\/516\/revisions"}],"wp:attachment":[{"href":"https:\/\/icu.ge\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=516"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/icu.ge\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=516"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/icu.ge\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=516"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}